Journal article
Complications of Massive Transfusion
Chest, Vol.137(1), pp.209-220
01/01/2010
DOI: 10.1378/chest.09-0252
PMID: 20051407
Abstract
Massive transfusion (MT) is a lifesaving treatment of hemorrhagic shock, but can be associated with significant complications. The lethal triad of acidosis, hypothermia, and coagulopathy associated with MT is associated with a high mortality rate. Other complications include hypothermia, acid/base derangements, electrolyte abnormalities (hypocalcemia, hypomagnesemia, hypokalemia, hyperkalemia), citrate toxicity, and transfusion-associated acute lung injury. Blood transfusion in trauma, surgery, and critical care has been identified as an independent predictor of multiple organ failure, systemic inflammatory response syndrome, increased infection, and increased mortality in multiple studies. Once definitive control of hemorrhage has been established, a restrictive approach to blood transfusion should be implemented to minimize further complications. CHEST 2010; 137(1):209-220
Details
- Title: Subtitle
- Complications of Massive Transfusion
- Creators
- Kristen C. Sihler - University of Michigan–Ann ArborLena M. Napolitano - University of Michigan–Ann Arbor
- Resource Type
- Journal article
- Publication Details
- Chest, Vol.137(1), pp.209-220
- Publisher
- Elsevier
- DOI
- 10.1378/chest.09-0252
- PMID
- 20051407
- ISSN
- 0012-3692
- eISSN
- 1931-3543
- Number of pages
- 12
- Language
- English
- Date published
- 01/01/2010
- Academic Unit
- Surgery
- Record Identifier
- 9984746241102771
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