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Complications related to third space endoscopic procedures
Journal article   Peer reviewed

Complications related to third space endoscopic procedures

Rami El Abiad, Munish Ashat and Mouen Khashab
Baillière's best practice & research. Clinical gastroenterology, Vol.71, 101908
08/2024
DOI: 10.1016/j.bpg.2024.101908
PMID: 39209411

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Abstract

Third space endoscopy (TSE) encompasses a breadth of procedures for the treatment of a variety of GI disorders. The widespread use of per-oral endoscopic myotomy (POEM) and its diversification to include extended indications and at locations other than the oesophagus has provided an insight into the potential complications encountered. The most common adverse events associated with POEM, the epitome of TSE procedures, include insufflation related injuries, bleeding, failure of mucosal barrier, infections, pain, blown out myotomy and gastroesophageal reflux disease. The purpose of this review is to highlight the pitfalls and to identify the risk factors that may lead to adverse events, and to recommend appropriate salvage interventions in the scope of the current evidence.
Adverse events Bleeding Complications Gas related injury Gastroesophageal reflux disease (GERD) Leak Per-Oral Endoscopic Myotomy Third space endoscopy

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