Composite Block Polymer-Microfabricated Silicon Nanoporous Membrane

Eric E Nuxoll; Marc A Hillmyer; Ruifang Wang; C Leighton; Ronald A Siegel

doi:10.1021/am900013v

Back

Composite Block Polymer-Microfabricated Silicon Nanoporous Membrane

Journal article

Peer reviewed

Composite Block Polymer-Microfabricated Silicon Nanoporous Membrane

Eric E Nuxoll, Marc A Hillmyer, Ruifang Wang, C Leighton and Ronald A Siegel

ACS applied materials & interfaces, Vol.1(4), pp.888-893

04/29/2009

DOI: 10.1021/am900013v

PMCID: PMC2772169

PMID: 20160882

Files and links (1)

url

https://www.ncbi.nlm.nih.gov/pmc/articles/2772169View

Open Access

Abstract

Block polymers offer an attractive route to densely-packed, monodisperse nanoscale pores. However, their fragility as thin films complicates their use as membranes. By integrating a block polymer film with a thin (100 μm) silicon substrate, we have developed a composite membrane providing both nanoscale size exclusion and fast transport of small molecules. Here we describe the fabrication of this membrane, evaluate its mechanical integrity, and demonstrate its transport properties for model solutes of large and small molecular weight. The ability to block large molecules without hindering smaller ones, coupled with the potential for surface modification of the polymer and the MEMS style of the support make this composite membrane an attractive candidate for interfacing implantable sensing and drug delivery devices with biological hosts.

MEMS

membrane

block polymer

size selectivity

nanoporous

Details

Title: Subtitle: Composite Block Polymer-Microfabricated Silicon Nanoporous Membrane
Creators: Eric E Nuxoll - Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
Marc A Hillmyer - Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
Ruifang Wang - Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
C Leighton - Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
Ronald A Siegel - Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
Resource Type: Journal article
Publication Details: ACS applied materials & interfaces, Vol.1(4), pp.888-893
DOI: 10.1021/am900013v
PMID: 20160882
PMCID: PMC2772169
NLM abbreviation: ACS Appl Mater Interfaces
ISSN: 1944-8244
eISSN: 1944-8252
Language: English
Date published: 04/29/2009
Academic Unit: Pharmaceutical Sciences and Experimental Therapeutics; Chemical and Biochemical Engineering
Record Identifier: 9984004095802771

Metrics

38 Record Views

51 Times Cited - Web of Science