Compositional and microhardness findings in tooth affected by X-linked hypophosphatemic rickets

Francisco-Samuel-Rodrigues Carvalho; Victor Pinheiro Feitosa; Cristiane-Sá Roriz Fonteles; Thyciana-Rodrigues Ribeiro; Bruno-Sousa Araújo; Alejandro-Pedro Ayala; Fábio-Wildson-Gurgel Costa

doi:10.4317/JCED.56945

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Compositional and microhardness findings in tooth affected by X-linked hypophosphatemic rickets

Journal article

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Compositional and microhardness findings in tooth affected by X-linked hypophosphatemic rickets

Francisco-Samuel-Rodrigues Carvalho, Victor Pinheiro Feitosa, Cristiane-Sá Roriz Fonteles, Thyciana-Rodrigues Ribeiro, Bruno-Sousa Araújo, Alejandro-Pedro Ayala and Fábio-Wildson-Gurgel Costa

Journal of clinical and experimental dentistry, Vol.12(7), pp.e688-e694

07/01/2020

DOI: 10.4317/JCED.56945

PMCID: PMC7462373

PMID: 32904979

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Abstract

This study aimed to evaluate the X-linked hypophosphatemic rickets (XLHR)-related compositional and microhardness tooth aspects. One affected and one non-affected teeth by XLHR were sectioned transversely, and each section was separated for Micro-Raman spectroscopy, Knoop microhardness and scanning electron microscopy with energy dispersive x-ray microanalysis (SEM-EDS). The outcomes of these analyses were assessed. Outcomes of Raman analysis of inorganic/organic components (~958/~1250+~1450 cm-1) and carbonate/phosphate (~1070/~958 cm-1) ratios showed areas of altered enamel and dentin (interglobular dentin, calcospherites, and mantle dentin) with an increase of inorganic content in the rickets tooth. Microhardness reduction was observed in the affected tooth, with a more evident drop in regions of mantle dentin, interglobular dentin, and calcospherites. SEM-EDS analysis showed demonstrated the absence of calcium and phosphorus in interglobular spaces. In conclusion, compositional and structural deficiencies were observed in deciduous tooth affected by XLHR. Also, it was observed the absence of hydroxyapatite in the interglobular dentin by using Raman spectroscopy analysis. Dentin, dentin permeability, X-linked hypophosphatemic rickets, tooth, tooth calcification, Raman spectroscopy.

Details

Title: Subtitle: Compositional and microhardness findings in tooth affected by X-linked hypophosphatemic rickets
Creators: Francisco-Samuel-Rodrigues Carvalho - Universidade Federal do Ceará
Victor Pinheiro Feitosa - University of Iowa, Operative Dentistry
Cristiane-Sá Roriz Fonteles - Universidade Federal do Ceará
Thyciana-Rodrigues Ribeiro - Universidade Federal do Ceará
Bruno-Sousa Araújo - Universidade Federal do Ceará
Alejandro-Pedro Ayala - Universidade Federal do Ceará
Fábio-Wildson-Gurgel Costa - Universidade Federal do Ceará
Resource Type: Journal article
Publication Details: Journal of clinical and experimental dentistry, Vol.12(7), pp.e688-e694
DOI: 10.4317/JCED.56945
PMID: 32904979
PMCID: PMC7462373
ISSN: 1989-5488
eISSN: 1989-5488
Language: English
Date published: 07/01/2020
Academic Unit: Operative Dentistry
Record Identifier: 9984654466002771

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