Comprehensive MR evaluation of renovascular disease in five breath holds

S O Schoenberg; M Essig; M Bock; H Hawighorst; M Sharafuddin; M V Knopp

doi:10.1002/(sici)1522-2586(199909)10:3<347::aid-jmri17>3.0.co;2-a

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Comprehensive MR evaluation of renovascular disease in five breath holds

Journal article

Peer reviewed

Comprehensive MR evaluation of renovascular disease in five breath holds

S O Schoenberg, M Essig, M Bock, H Hawighorst, M Sharafuddin and M V Knopp

Journal of magnetic resonance imaging, Vol.10(3), pp.347-356

09/1999

DOI: 10.1002/(sici)1522-2586(199909)10:3<347::aid-jmri17>3.0.co;2-a

PMID: 10508296

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Abstract

To detect a renal artery stenosis and assess its hemodynamic and functional significance in five breath holds. In a single MR exam, T1 weighted FLASH and T2 weighted fast spin echo techniques are used to assess renal morphology, multiphase 3D gadolinium (Gd) MRA to evaluate the renal arteries, and a segmented EPI cine phase-contrast technique to measure renal artery blood flow. A standardized image analysis is performed to assess kidney size, corticomedullar differentiation (CMD), parenchymal enhancement, the degree of renal artery stenosis, abnormalities in blood flow pattern, and any associated abdominal vascular disease. Multiphase 3D-Gd-MRA accurately assesses atherosclerotic renal artery disease particularly in the presence of an associated aortic aneurysm. Delayed parenchymal enhancement, loss of CMD, and decrease in kidney size can be detected. In combination with decreased systolic velocity components, the diagnosis of a hemodynamically and functionally significant stenosis can be made. High-resolution single-phase 3D-Gd-MRA is preferable for evaluation of fibromuscular dysplasia or hypoplastic vessels. The combination of different breath hold techniques in a single, standardized MR exam allows to detect the hemodynamic and functional significance of a renal artery stenosis.

Hemodynamics

Humans

Middle Aged

Renal Artery Obstruction - physiopathology

Gadolinium

Male

Renal Artery Obstruction - diagnosis

Contrast Media

Image Processing, Computer-Assisted

Magnetic Resonance Angiography - methods

Aged

Image Enhancement - methods

Renal Artery Obstruction - pathology

Details

Title: Subtitle: Comprehensive MR evaluation of renovascular disease in five breath holds
Creators: S O Schoenberg - Department of Radiology, German Cancer Research Center (dkfz), Heidelberg, Germany. schoenbe@umich.edu
M Essig
M Bock
H Hawighorst
M Sharafuddin
M V Knopp
Resource Type: Journal article
Publication Details: Journal of magnetic resonance imaging, Vol.10(3), pp.347-356
Publisher: United States
DOI: 10.1002/(sici)1522-2586(199909)10:3<347::aid-jmri17>3.0.co;2-a
PMID: 10508296
ISSN: 1053-1807
eISSN: 1522-2586
Language: English
Date published: 09/1999
Academic Unit: Radiology; Surgery
Record Identifier: 9984051552302771

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