Journal article
Computational methods and results for structured multiscale models of tumor invasion
Multiscale modeling & simulation, Vol.5(1), pp.1-20
2006
DOI: 10.1137/050629215
Abstract
We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the models, and discuss the scientific-computing methodology used to solve the model equations. The models and methodology presented in this paper form the basis for developing and treating increasingly complex, mechanistic models of tumor invasion that will be more predictive and less phenomenological. Because many of the features of the cancer models, such as taxis, aging, and growth, are seen in other biological systems, the models and methods discussed here also provide a template for handling a broader range of biological problems.
Details
- Title: Subtitle
- Computational methods and results for structured multiscale models of tumor invasion
- Creators
- Bruce P AyatiGlenn F WebbAlexander R.A Anderson
- Resource Type
- Journal article
- Publication Details
- Multiscale modeling & simulation, Vol.5(1), pp.1-20
- DOI
- 10.1137/050629215
- ISSN
- 1540-3459
- eISSN
- 1540-3467
- Language
- English
- Date published
- 2006
- Academic Unit
- Orthopedics and Rehabilitation; Mathematics
- Record Identifier
- 9983985985202771
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