Computational neural modeling of speech motor control in childhood apraxia of speech (CAS)

Hayo Terband; Ben Maassen; Frank H Guenther; Jonathan Brumberg

doi:10.1044/1092-4388(2009/07-0283)

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Computational neural modeling of speech motor control in childhood apraxia of speech (CAS)

Journal article

Open access

Peer reviewed

Computational neural modeling of speech motor control in childhood apraxia of speech (CAS)

Hayo Terband, Ben Maassen, Frank H Guenther and Jonathan Brumberg

Journal of speech, language, and hearing research, Vol.52(6), pp.1595-1609

12/2009

DOI: 10.1044/1092-4388(2009/07-0283)

PMCID: PMC2959199

PMID: 19951927

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https://www.ncbi.nlm.nih.gov/pmc/articles/2959199View

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Abstract

Childhood apraxia of speech (CAS) has been associated with a wide variety of diagnostic descriptions and has been shown to involve different symptoms during successive stages of development. In the present study, the authors attempted to associate the symptoms of CAS in a particular developmental stage with particular information-processing deficits by using computational modeling with the Directions Into Velocities of Articulators (DIVA) model. The hypothesis was that the speech production system in CAS suffers from poor feed-forward control and, consequently, an increased reliance on the feedback control subsystem. In a series of computer simulations, the authors systematically varied the ratio between feed-forward and feedback control during production attempts in the acquisition of feed-forward motor commands. The simulations were evaluated acoustically on 4 selected key symptoms of CAS. Results showed that increasing the reliance on feedback control causes increased severity of these 4 symptoms of CAS: deviant coarticulation, speech sound distortion, searching articulation, and increased variability. The findings support the idea that the key symptoms found in CAS could result from an increased reliance on feedback control due to poor feed-forward commands. Two possible root causes of degraded feed-forward control in CAS are discussed: reduced somatosensory information and increased levels of neural noise.

Acoustic Stimulation

Apraxias - physiopathology

Brain - physiopathology

Child

Computer Simulation

Feedback

Humans

Models, Neurological

Motor Activity - physiology

Phonetics

Psychomotor Performance - physiology

Speech - physiology

Speech Disorders - physiopathology

Speech Perception - physiology

Details

Title: Subtitle: Computational neural modeling of speech motor control in childhood apraxia of speech (CAS)
Creators: Hayo Terband - Radboud University Medical Center
Ben Maassen - Radboud University Medical Center
Frank H Guenther - Massachusetts Institute of Technology
Jonathan Brumberg - Boston University
Resource Type: Journal article
Publication Details: Journal of speech, language, and hearing research, Vol.52(6), pp.1595-1609
DOI: 10.1044/1092-4388(2009/07-0283)
PMID: 19951927
PMCID: PMC2959199
NLM abbreviation: J Speech Lang Hear Res
ISSN: 1092-4388
eISSN: 1558-9102
Grant note: R01 DC002852 / NIDCD NIH HHS R01 DC002852-14 / NIDCD NIH HHS R01 DC02852 / NIDCD NIH HHS
Language: English
Date published: 12/2009
Academic Unit: Communication Sciences and Disorders
Record Identifier: 9984258846702771

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