Computed Tomography: State-of-the-Art Advancements in Musculoskeletal Imaging

Hamza Ahmed Ibad; Cesar de Cesar Netto; Delaram Shakoor; Alejandro Sisniega; Stephen Z Liu; Jeffrey H Siewerdsen; John A Carrino; Wojciech Zbijewski; Shadpour Demehri

doi:10.1097/RLI.0000000000000908

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Computed Tomography: State-of-the-Art Advancements in Musculoskeletal Imaging

Journal article

Open access

Peer reviewed

Computed Tomography: State-of-the-Art Advancements in Musculoskeletal Imaging

Hamza Ahmed Ibad, Cesar de Cesar Netto, Delaram Shakoor, Alejandro Sisniega, Stephen Z Liu, Jeffrey H Siewerdsen, John A Carrino, Wojciech Zbijewski and Shadpour Demehri

Investigative radiology, Vol.58(1), pp.99-110

01/2023

DOI: 10.1097/RLI.0000000000000908

PMCID: PMC9742155

PMID: 35976763

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https://www.ncbi.nlm.nih.gov/pmc/articles/9742155View

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Abstract

Although musculoskeletal magnetic resonance imaging (MRI) plays a dominant role in characterizing abnormalities, novel computed tomography (CT) techniques have found an emerging niche in several scenarios such as trauma, gout, and the characterization of pathologic biomechanical states during motion and weight-bearing. Recent developments and advancements in the field of musculoskeletal CT include 4-dimensional, cone-beam (CB), and dual-energy (DE) CT. Four-dimensional CT has the potential to quantify biomechanical derangements of peripheral joints in different joint positions to diagnose and characterize patellofemoral instability, scapholunate ligamentous injuries, and syndesmotic injuries. Cone-beam CT provides an opportunity to image peripheral joints during weight-bearing, augmenting the diagnosis and characterization of disease processes. Emerging CBCT technologies improved spatial resolution for osseous microstructures in the quantitative analysis of osteoarthritis-related subchondral bone changes, trauma, and fracture healing. Dual-energy CT-based material decomposition visualizes and quantifies monosodium urate crystals in gout, bone marrow edema in traumatic and nontraumatic fractures, and neoplastic disease. Recently, DE techniques have been applied to CBCT, contributing to increased image quality in contrast-enhanced arthrography, bone densitometry, and bone marrow imaging. This review describes 4-dimensional CT, CBCT, and DECT advances, current logistical limitations, and prospects for each technique.

Details

Title: Subtitle: Computed Tomography: State-of-the-Art Advancements in Musculoskeletal Imaging
Creators: Hamza Ahmed Ibad - Johns Hopkins University School of Medicine
Cesar de Cesar Netto - University of Iowa
Delaram Shakoor - Yale School of Medicine
Alejandro Sisniega - Johns Hopkins University
Stephen Z Liu - Johns Hopkins University
Jeffrey H Siewerdsen - Johns Hopkins University
John A Carrino - Hospital for Special Surgery
Wojciech Zbijewski - Johns Hopkins University
Shadpour Demehri - Johns Hopkins University School of Medicine
Resource Type: Journal article
Publication Details: Investigative radiology, Vol.58(1), pp.99-110
DOI: 10.1097/RLI.0000000000000908
PMID: 35976763
PMCID: PMC9742155
NLM abbreviation: Invest Radiol
eISSN: 1536-0210
Grant note: R01 EB025470 / NIBIB NIH HHS
Language: English
Date published: 01/2023
Academic Unit: Orthopedics and Rehabilitation
Record Identifier: 9984322740902771

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