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Computer-based image analysis in breast pathology
Journal article   Open access   Peer reviewed

Computer-based image analysis in breast pathology

Ziba Gandomkar, Patrick C Brennan and Claudia Mello-Thoms
Journal of pathology informatics, Vol.7(1), pp.43-43
01/29/2016
DOI: 10.4103/2153-3539.192814
PMCID: PMC5100199
PMID: 28066683
url
https://doi.org/10.4103/2153-3539.192814View
Published (Version of record) Open Access

Abstract

Whole slide imaging (WSI) has the potential to be utilized in telepathology, teleconsultation, quality assurance, clinical education, and digital image analysis to aid pathologists. In this paper, the potential added benefits of computer-assisted image analysis in breast pathology are reviewed and discussed. One of the major advantages of WSI systems is the possibility of doing computer-based image analysis on the digital slides. The purpose of computer-assisted analysis of breast virtual slides can be (i) segmentation of desired regions or objects such as diagnostically relevant areas, epithelial nuclei, lymphocyte cells, tubules, and mitotic figures, (ii) classification of breast slides based on breast cancer (BCa) grades, the invasive potential of tumors, or cancer subtypes, (iii) prognosis of BCa, or (iv) immunohistochemical quantification. While encouraging results have been achieved in this area, further progress is still required to make computer-based image analysis of breast virtual slides acceptable for clinical practice.
whole slide imaging Breast pathology Review breast virtual slides image analysis

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