Journal article
Cone degeneration in two Shih Tzu dogs: clinical and genetic investigation
Ciência rural, Vol.55(8), e20240397
06/01/2025
DOI: 10.1590/0103-8478cr20240397
Abstract
Two cases of cone degeneration in adult Shih Tzu canine patients are reported herein. Definitive diagnosis was made based on the ophthalmic examination finding, typical clinical signs, and characteristic electroretinography results that demonstrated normal rod function and absence of recordable cone function. Sanger sequencing of the entire coding sequence of the cyclic nucleotide gated channel β3 (CNGB3) gene did not reveal disease causing variants in these dogs. To the authors’ knowledge, this is the first report of clinical, electroretinographic and genetic investigation of cone degeneration in Shih Tzu.
Details
- Title: Subtitle
- Cone degeneration in two Shih Tzu dogs: clinical and genetic investigation
- Creators
- Tatiana Assunção de Moraes - Universidade de São PauloAngélica de Mendonça Vaz Safatle - Associação Brasileira de Oncologia VeterináriaErin Burnight - University of IowaBudd Tucker - University of IowaGil Ben-Shlomo - Cornell University
- Resource Type
- Journal article
- Publication Details
- Ciência rural, Vol.55(8), e20240397
- DOI
- 10.1590/0103-8478cr20240397
- ISSN
- 0103-8478
- eISSN
- 1678-4596
- Publisher
- Universidade Federal de Santa Maria
- Language
- English
- Date published
- 06/01/2025
- Academic Unit
- The University of Iowa Institute for Vision Research; Neuroscience and Pharmacology; Ophthalmology and Visual Sciences
- Record Identifier
- 9984833628702771
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