Journal article
Congenital Generalized Lipodystrophy in a Division 1 Female Sprinter
Clinical journal of sport medicine, Vol.34(4), pp.396-399
07/01/2024
DOI: 10.1097/JSM.0000000000001214
PMID: 38914100
Abstract
A 21-year-old African American Division 1 female sprinter presented with 3-weeks history of right great toe and forefoot pain, fatigue, and a 30-day continuous menstrual cycle despite implanted etonogestrel (Nexplanon) inserted 3 years prior. An magnetic resonance imagine (MRI) identified likely stress fracture of the second metatarsal base with a diffusely low T1 signal indicating hyperactive red marrow. Due to persistent pain, a follow-up MRI was ordered 6 months later and indicated serous atrophy of the bone marrow, prompting a further metabolic workup notable for triglycerides exceeding 4000 mg/dL and a hemoglobin A1c of 10.9%. This case highlights the manifestation of a rare congenital lipodystrophy that initially presented as a relatively classic stress fracture and metrorrhagia in a female athlete.
Details
- Title: Subtitle
- Congenital Generalized Lipodystrophy in a Division 1 Female Sprinter
- Creators
- Kevin T. Schleich - University of IowaKira D. Novakofski - Mayo Clinic Health SystemTimothy W. Thomsen - University of IowaLisa Woodroffe - University of IowaTyler G. Slayman - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Clinical journal of sport medicine, Vol.34(4), pp.396-399
- DOI
- 10.1097/JSM.0000000000001214
- PMID
- 38914100
- ISSN
- 1050-642X
- eISSN
- 1536-3724
- Language
- English
- Date published
- 07/01/2024
- Academic Unit
- Stead Family Department of Pediatrics; Emergency Medicine; Orthopedics and Rehabilitation; Family and Community Medicine; General Pediatrics and Adolescent Medicine
- Record Identifier
- 9984648357802771
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