Journal article
Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease
Journal of cerebral blood flow and metabolism, Vol.38(9), pp.1391-1417
09/2018
DOI: 10.1177/0271678X17721830
PMCID: PMC6125970
PMID: 28816594
Abstract
Cerebrovascular disease (CVD) remains a leading cause of death and the leading cause of adult disability in most developed countries. This work summarizes state-of-the-art, and possible future, diagnostic and evaluation approaches in multiple stages of CVD, including (i) visualization of sub-clinical disease processes, (ii) acute stroke theranostics, and (iii) characterization of post-stroke recovery mechanisms. Underlying pathophysiology as it relates to large vessel steno-occlusive disease and the impact of this macrovascular disease on tissue-level viability, hemodynamics (cerebral blood flow, cerebral blood volume, and mean transit time), and metabolism (cerebral metabolic rate of oxygen consumption and pH) are also discussed in the context of emerging neuroimaging protocols with sensitivity to these factors. The overall purpose is to highlight advancements in stroke care and diagnostics and to provide a general overview of emerging research topics that have potential for reducing morbidity in multiple areas of CVD.
Details
- Title: Subtitle
- Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease
- Creators
- Manus J Donahue - Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USAEric Achten - Department of Radiology and Nuclear Medicine, Universiteit Gent, Gent, BelgiumPetrice M Cogswell - Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USAFrank-Erik De Leeuw - Radboud University, Nijmegen Medical Center, Donders Institute Brain Cognition & Behaviour, Center for Neuroscience, Department of Neurology, Nijmegen, The NetherlandsColin P Derdeyn - Department of Radiology and Neurology, University of Iowa, Iowa City, IA, USARick M Dijkhuizen - Biomedical MR Imaging and Spectroscopy Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht, The NetherlandsAudrey P Fan - Department of Radiology, Stanford University, Stanford, CA, USARashid Ghaznawi - Department of Radiology, University Medical Center Utrecht, Utrecht, The NetherlandsJeremy J Heit - Department of Radiology, Neuroimaging and Neurointervention Division, Stanford University, CA, USAM Arfan Ikram - Department of Epidemiology, Erasmus MC, Rotterdam, The NetherlandsPeter Jezzard - Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UKLori C Jordan - Department of Pediatrics, Division of Pediatric Neurology, Vanderbilt University Medical Center, Nashville, TN, USAEric Jouvent - Department of Neurology, AP-HP, Lariboisière Hospital, Paris, FranceLinda Knutsson - Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USARichard Leigh - National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USADavid S Liebeskind - Neurovascular Imaging Research Core, UCLA, Los Angeles, CA, USAWeili Lin - Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAThomas W Okell - Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UKAdnan I Qureshi - Department of Neurology, Zeenat Qureshi Stroke Institute, St. Cloud, MN, USACharlotte J Stagg - Oxford Centre for Human Brain Activity, University of Oxford, Oxford, UKMatthias JP van Osch - Department of Radiology, Leiden Medical Center, Leiden, The NetherlandsPeter CM van Zijl - Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USAJennifer M Watchmaker - Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USAMax Wintermark - Department of Radiology, Neuroimaging and Neurointervention Division, Stanford University, CA, USAOna Wu - Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USAGreg Zaharchuk - Department of Radiology, Neuroimaging and Neurointervention Division, Stanford University, CA, USAJinyuan Zhou - Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USAJeroen Hendrikse - Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
- Resource Type
- Journal article
- Publication Details
- Journal of cerebral blood flow and metabolism, Vol.38(9), pp.1391-1417
- Publisher
- SAGE Publications; Sage UK: London, England
- DOI
- 10.1177/0271678X17721830
- PMID
- 28816594
- PMCID
- PMC6125970
- ISSN
- 0271-678X
- eISSN
- 1559-7016
- Language
- English
- Date published
- 09/2018
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020643702771
Metrics
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