Considerations on optimal fluoride intake using dental fluorosis and dental caries outcomes--a longitudinal study

John J Warren; Steven M Levy; Barbara Broffitt; Joseph E Cavanaugh; Michael J Kanellis; Karin Weber-Gasparoni

doi:10.1111/j.1752-7325.2008.00108.x

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Considerations on optimal fluoride intake using dental fluorosis and dental caries outcomes--a longitudinal study

Journal article

Open access

Peer reviewed

Considerations on optimal fluoride intake using dental fluorosis and dental caries outcomes--a longitudinal study

John J Warren, Steven M Levy, Barbara Broffitt, Joseph E Cavanaugh, Michael J Kanellis and Karin Weber-Gasparoni

Journal of public health dentistry, Vol.69(2), pp.111-115

2009

DOI: 10.1111/j.1752-7325.2008.00108.x

PMCID: PMC4350236

PMID: 19054310

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http://doi.org/10.1111/j.1752-7325.2008.00108.xView

Open Access

Abstract

The "optimal" intake of fluoride has been widely accepted for decades as between 0.05 and 0.07 mg fluoride per kilogram of body weight (mg F/kg bw) but is based on limited scientific evidence. The purpose of this paper is to present longitudinal fluoride intake data for children free of dental fluorosis in the early-erupting permanent dentition and free of dental caries in both the primary and early-erupting permanent teeth as an estimate of optimal fluoride intake. Data on fluoride ingestion were obtained from parents of 602 Iowa Fluoride Study children through periodic questionnaires at the ages of 6 weeks; 3, 6, 9, 12, 16, 20, 24, 28, 32, and 36 months; and then at 6-month intervals thereafter. Estimates of total fluoride intake at each time point were made by summing amounts from water, dentifrice, and supplements, as well as other foods and beverages made with, or containing, water. Caries data were obtained from examinations of children at ages 5 and 9 years, whereas fluorosis data were obtained from examinations of children only at age 9 years. The estimated mean daily fluoride intake for those children with no caries history and no fluorosis at age 9 years was at, or below, 0.05 mg F/kg bw for nearly all time points through the first 48 months of life, and this level declined thereafter. Children with caries had generally slightly less intakes, whereas those with fluorosis generally had slightly higher intakes. Given the overlap among caries/fluorosis groups in mean fluoride intake and extreme variability in individual fluoride intakes, firmly recommending an "optimal" fluoride intake is problematic.

Outcome Assessment (Health Care)

Humans

Fluorosis, Dental - physiopathology

Surveys and Questionnaires

Longitudinal Studies

Cohort Studies

Dental Caries - physiopathology

Fluorides - administration & dosage

Details

Title: Subtitle: Considerations on optimal fluoride intake using dental fluorosis and dental caries outcomes--a longitudinal study
Creators: John J Warren - Department of Preventive & Community Dentistry, University of Iowa, Iowa City, IA 52242-1010, USA. john-warren@uiowa.edu
Steven M Levy
Barbara Broffitt
Joseph E Cavanaugh
Michael J Kanellis
Karin Weber-Gasparoni
Resource Type: Journal article
Publication Details: Journal of public health dentistry, Vol.69(2), pp.111-115
DOI: 10.1111/j.1752-7325.2008.00108.x
PMID: 19054310
PMCID: PMC4350236
NLM abbreviation: J Public Health Dent
ISSN: 0022-4006
eISSN: 1752-7325
Publisher: United States
Grant note: R01 DE009551 / NIDCR NIH HHS R01 DE012101 / NIDCR NIH HHS
Language: English
Date published: 2009
Academic Unit: Statistics and Actuarial Science; Preventive and Community Dentistry; Epidemiology; Dental Clinic Administration; Biostatistics; Pediatric Dentistry; Injury Prevention Research Center
Record Identifier: 9983917775602771

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