Considerazioni su prove di biocompatibilità “in vitro” ed “in vivo” di alcuni cementi endodontici

Luciano Fonzi; Alberto Gasparoni; Laura Capezzuoli; Sandra Carboncini; Massimo Belli; Vassiolios Kaitsas

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Considerazioni su prove di biocompatibilità “in vitro” ed “in vivo” di alcuni cementi endodontici

Journal article

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Considerazioni su prove di biocompatibilità “in vitro” ed “in vivo” di alcuni cementi endodontici

Luciano Fonzi, Alberto Gasparoni, Laura Capezzuoli, Sandra Carboncini, Massimo Belli and Vassiolios Kaitsas

Giornale italiano di endodonzia, Vol.5(3), pp.70-78

1991

PMID: 1777682

Appears in Diamond Open Access

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Abstract

The major goal of endodontic therapy has been achieved by condensing filling materials into the root canal. It is not uncommon to find excess material in the periapical tissue. It therefore becomes obligatory to use filling materials that have acceptable biocompatibility. The purpose of this investigation was to obtain a "toxicity profile" of some root canal materials and to compare our observations to study results found in literature. Gutta-percha and five endodontic filling cements were tested in vivo and in vitro. The in vivo biocompatibility involved the placement of the test material in 10 mm teflon tubes with an outer diameter of 1,3 mm which were then implanted subcutaneously into rats. The implants were left in situ for periods of 30 and 90 days. The hemolysis test was used for in vitro evaluations. The histological examination showed cellular responses of different intensity and extent. In some cases severe infiltration of inflammatory cells and areas with necrostis were observed. As a result, the root canal materials evaluated showed slight, moderate, and severe reactions, therefore, a different pattern in tissue response.

Dentistry

Details

Title: Subtitle: Considerazioni su prove di biocompatibilità “in vitro” ed “in vivo” di alcuni cementi endodontici
Creators: Luciano Fonzi
Alberto Gasparoni
Laura Capezzuoli
Sandra Carboncini
Massimo Belli
Vassiolios Kaitsas
Resource Type: Journal article
Publication Details: Giornale italiano di endodonzia, Vol.5(3), pp.70-78
PMID: 1777682
ISSN: 1121-4171
Alternative title: Biocompatibility in vitro and in vivo of some endodontic materials
Language: Italian
Date published: 1991
Academic Unit: Oral Pathology, Radiology and Medicine; Dental Clinic Administration
Record Identifier: 9984367626402771

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