Journal article
Construction of 1,2,4-Triazole Derivatives via Cyclocondensation of Alkylidene Dihydropyridines and Aryldiazonium Salts
Organic letters, Vol.18(22), pp.5916-5919
11/18/2016
DOI: 10.1021/acs.orglett.6b03019
PMID: 27934495
Abstract
Alkylidene dihydropyridines (anhydrobases) prepared via dearomatization of N-acylated 4-(aminomethyl)pyridines participate in [3 + 2] cyclocondensation reactions with aryldiazonium cations to afford substituted 1,2,4-triazolium salts or neutral 1,2,4-triazoles in high isolated yield. The reaction proceeds in the presence of a variety of N-acyl groups and aryl-susbtituted diazonium salts and offers a general route to pyridyl-substituted 1,2,4-triazoles.
Details
- Title: Subtitle
- Construction of 1,2,4-Triazole Derivatives via Cyclocondensation of Alkylidene Dihydropyridines and Aryldiazonium Salts
- Creators
- Madhur S JoshiF. Christopher Pigge
- Resource Type
- Journal article
- Publication Details
- Organic letters, Vol.18(22), pp.5916-5919
- Publisher
- American Chemical Society
- DOI
- 10.1021/acs.orglett.6b03019
- PMID
- 27934495
- ISSN
- 1523-7060
- eISSN
- 1523-7052
- Grant note
- DOI: 10.13039/100000165, name: Division of Chemistry, award: CHE-1265488
- Language
- English
- Date published
- 11/18/2016
- Academic Unit
- Radiology; Chemistry
- Record Identifier
- 9983985847502771
Metrics
10 Record Views