Contamination Levels in Blood Samples Drawn from the Injection Intravenous Line

Laura L.Boles Ponto; Michael M Graham; John C Richmond; Christine A Ward; Dean A Clermont; Beth A Schmitt; JoAnn Clark; Amy Conklin; Lea Weldon; G.Leonard Watkins; Mark T Madsen; Richard D Hichwa

doi:10.1016/S1536-1632(02)00121-X

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Contamination Levels in Blood Samples Drawn from the Injection Intravenous Line

Journal article

Peer reviewed

Contamination Levels in Blood Samples Drawn from the Injection Intravenous Line

Laura L.Boles Ponto, Michael M Graham, John C Richmond, Christine A Ward, Dean A Clermont, Beth A Schmitt, JoAnn Clark, Amy Conklin, Lea Weldon, G.Leonard Watkins, …

Molecular imaging and biology, Vol.4(6), pp.410-414

2002

DOI: 10.1016/S1536-1632(02)00121-X

PMID: 14537105

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Abstract

Purpose: Securing two intravenous lines, one for injection and one for blood sampling, can be nearly impossible in compromised patients, therefore, a need exists to quantify the potential error when simplified techniques are employed. Method: Two venous catheters were placed. 2-deoxy-2-[ 18F]fluoro-glucose (FDG) was infused through one of the catheters. Venous blood samples were drawn from each line. Triplicate aliquots of plasma were analyzed in duplicate. Results: Concentrations from the infusion line were 2.0% higher than the concentrations from the noninfusion line. The average error was 3.3%, 2.0%, and 0.7% higher for the first, second, and third samples, respectively. Conclusions: Blood sampling through the infusion catheter is a viable alternative to the placement of separate venous catheters. Sampling from the injection catheter, even with tubing flush and replacement, will potentially incur small (generally < 10%) overestimations in concentration in initial samples. Subsequent sampling reduces the error to essentially zero by the third sample.

FDG

Positron emission tomography

2-deoxy-2-[ 18 F]fluoro-D-glucose

Blood sampling

Details

Title: Subtitle: Contamination Levels in Blood Samples Drawn from the Injection Intravenous Line
Creators: Laura L.Boles Ponto
Michael M Graham
John C Richmond
Christine A Ward
Dean A Clermont
Beth A Schmitt
JoAnn Clark
Amy Conklin
Lea Weldon
G.Leonard Watkins
Mark T Madsen
Richard D Hichwa
Resource Type: Journal article
Publication Details: Molecular imaging and biology, Vol.4(6), pp.410-414
Publisher: Elsevier Inc
DOI: 10.1016/S1536-1632(02)00121-X
PMID: 14537105
ISSN: 1536-1632
eISSN: 1860-2002
Language: English
Date published: 2002
Academic Unit: Radiology; Research Administration; Pharmaceutical Sciences and Experimental Therapeutics; Physics and Astronomy; Radiation Oncology
Record Identifier: 9984047718002771

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