Continuous glucose monitoring in children with type 1 diabetes

Bruce Buckingham; Roy W Beck; William V Tamborlane; Dongyuan Xing; Craig Kollman; Rosanna Fiallo-Scharer; Nelly Mauras; Katrina J Ruedy; Michael Tansey; Stuart A Weinzimer; Tim Wysocki; Diabetes Research in Children Network (DirecNet) Study Group

doi:10.1016/j.jpeds.2007.03.047

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Continuous glucose monitoring in children with type 1 diabetes

Journal article

Open access

Peer reviewed

Continuous glucose monitoring in children with type 1 diabetes

Bruce Buckingham, Roy W Beck, William V Tamborlane, Dongyuan Xing, Craig Kollman, Rosanna Fiallo-Scharer, Nelly Mauras, Katrina J Ruedy, Michael Tansey, Stuart A Weinzimer, …

The Journal of pediatrics, Vol.151(4), pp.388-393.e2

10/2007

DOI: 10.1016/j.jpeds.2007.03.047

PMCID: PMC2045068

PMID: 17889075

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https://doi.org/10.1016/j.jpeds.2007.03.047View

Published (Version of record) Open Access

Abstract

To examine the feasibility of daily use of a continuous glucose monitor, the FreeStyle Navigator Continuous Glucose Monitoring System ("Navigator"), in children with type 1 diabetes (T1D). After a masked Navigator was used for 4 to 7 days to establish a baseline level of glycemic control, 30 insulin pump users with T1D (average age 11.2 years) were asked to use the Navigator daily for 13 weeks. Subjects averaged 149 h/wk of Navigator use during the first 4 weeks, which decreased slightly to 134 h/wk during weeks 9 to 13 (P = .006). Mean hemoglobin A1c improved from 7.1% at baseline to 6.8% at 13 weeks (P = .02), and the percentage of glucose values between 71 and 180 mg/dL increased from 52% to 60% (P = .01). Subjects and parents reported high satisfaction with the Navigator on the Continuous Glucose Monitor Satisfaction Scale. Two subjects had severe skin reactions related to sensor mount adhesive. This study indicates that incorporating real-time continuous glucose monitoring into the daily treatment of children with T1D is feasible. The results provide a compelling rationale for conducting a randomized trial of daily use of a continuous glucose monitor in children with T1D.

Monitoring, Ambulatory - instrumentation

Glycated Hemoglobin A - metabolism

Humans

Child, Preschool

Male

Diabetes Mellitus, Type 1 - therapy

Feasibility Studies

Patient Satisfaction

Pilot Projects

Blood Glucose Self-Monitoring - adverse effects

Monitoring, Ambulatory - adverse effects

Diabetes Mellitus, Type 1 - blood

Adolescent

Female

Insulin Infusion Systems

Blood Glucose Self-Monitoring - instrumentation

Child

Details

Title: Subtitle: Continuous glucose monitoring in children with type 1 diabetes
Creators: Bruce Buckingham
Roy W Beck
William V Tamborlane
Dongyuan Xing
Craig Kollman
Rosanna Fiallo-Scharer
Nelly Mauras
Katrina J Ruedy
Michael Tansey
Stuart A Weinzimer
Tim Wysocki
Diabetes Research in Children Network (DirecNet) Study Group
Resource Type: Journal article
Publication Details: The Journal of pediatrics, Vol.151(4), pp.388-393.e2
DOI: 10.1016/j.jpeds.2007.03.047
PMID: 17889075
PMCID: PMC2045068
ISSN: 0022-3476
eISSN: 1097-6833
Grant note: M01 RR006022-10 / NCRR NIH HHS U10 HD041915-01 / NICHD NIH HHS U10 HD041906 / NICHD NIH HHS U10 HD041919-01 / NICHD NIH HHS M01 RR000069 / NCRR NIH HHS U10 HD041918-01 / NICHD NIH HHS M01 RR000070 / NCRR NIH HHS M01 RR000059-42 / NCRR NIH HHS U10 HD041918 / NICHD NIH HHS U10 HD041906-01 / NICHD NIH HHS U10 HD041908-01 / NICHD NIH HHS U10 HD041915 / NICHD NIH HHS U01 HD041890-01 / NICHD NIH HHS U10 HD041908 / NICHD NIH HHS U01 HD041890 / NICHD NIH HHS M01 RR000070-37 / NCRR NIH HHS M01 RR000069-37 / NCRR NIH HHS
Language: English
Date published: 10/2007
Academic Unit: Endocrinology and Diabetes; Stead Family Department of Pediatrics; Fraternal Order of Eagles Diabetes Research Center
Record Identifier: 9984093497902771

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