Continuous warm blood cardioplegia: a new technique for myocardial protection

A Karim Jabr; S STRAUS; R BREWSTER; R RODRIGUEZ; A PANOS; B HIEB; J PERRY; J DAUGHARTHY

doi:10.1051/ject/1990223107

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Continuous warm blood cardioplegia: a new technique for myocardial protection

Journal article

Open access

Continuous warm blood cardioplegia: a new technique for myocardial protection

A Karim Jabr, S STRAUS, R BREWSTER, R RODRIGUEZ, A PANOS, B HIEB, J PERRY and J DAUGHARTHY

The Journal of extra-corporeal technology, Vol.22(3), pp.107-109

1990

DOI: 10.1051/ject/1990223107

PMID: 10149012

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Abstract

Hypothermia is used to prolong the safe period of ischemic arrest by reducing the heart's oxygen demands. Due to this effect, hypothermia has been the fundamental component of most methods of myocardial protection during cardiac surgery. However, hypothermia has a number of unwanted side effects, such as detrimental effects on enzyme function, energy generation, and cell membranes. Since electromechanical arrest accounts for 90% of myocardial oxygen consumption, arresting the heart with chemical cardioplegia will reduce O2 consumption dramatically. Therefore, if the resting (arrested) heart is continuously perfused with oxygenated blood cardioplegia, one can easily provide the remaining 10% of O2 that it requires. Under these conditions, the need for hypothermia becomes questionable. In this paper, we describe the perfusionist's experience using the antegrade and retrograde technique of continuous warm blood cardioplegia.

Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy

Biological and medical sciences

Medical sciences

Details

Title: Subtitle: Continuous warm blood cardioplegia: a new technique for myocardial protection
Creators: A Karim Jabr - Cardio-Pulmonary Resources, Las Vegas NV 89104, United States
S STRAUS - Cardio-Pulmonary Resources, Las Vegas NV 89104, United States
R BREWSTER - Cardio-Pulmonary Resources, Las Vegas NV 89104, United States
R RODRIGUEZ - Cardio-Pulmonary Resources, Las Vegas NV 89104, United States
A PANOS - Cardio-Pulmonary Resources, Las Vegas NV 89104, United States
B HIEB - Cardio-Pulmonary Resources, Las Vegas NV 89104, United States
J PERRY - Cardio-Pulmonary Resources, Las Vegas NV 89104, United States
J DAUGHARTHY - Cardio-Pulmonary Resources, Las Vegas NV 89104, United States
Resource Type: Journal article
Publication Details: The Journal of extra-corporeal technology, Vol.22(3), pp.107-109
DOI: 10.1051/ject/1990223107
PMID: 10149012
NLM abbreviation: J Extra Corpor Technol
ISSN: 0022-1058
Publisher: American Society of Extra-Corporeal Technology; Reston, VA
Language: English
Date published: 1990
Academic Unit: Surgery; Cardiothoracic Surgery
Record Identifier: 9984051524802771

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