Journal article
Contractile Properties of Human Skeletal Muscle: Normal and Thyroid Disease
Archives of neurology (Chicago), Vol.25(6), pp.535-546
12/01/1971
DOI: 10.1001/archneur.1971.00490060069007
PMID: 5115554
Abstract
Active state duration and active state intensities of shortening and load-bearing were determined in the adductor pollicis muscle of 20 normal subjects, and seven hyperthyroid and four hypothyroid patients. Normal subjects showed a marked posttetanic and staircase twitch potentiation related primarily to an increase in active state intensity of shortening. In hyperthyroidism, active state duration in the unconditioned twitch was shortened while in hypothyroidism it was prolonged. Active state intensity of load-bearing was normal in hyperthyroidism (five of seven patients) and decreased in hypothyroidism (three of four patients). After repetitive stimulation (tetanus and staircase), both groups showed either a less than normal twitch potentiation (less than normal increase of active state intensity of shortening) or twitch depression below the control level (decreased active state duration without normal increase of active state intensity of shortening).
Details
- Title: Subtitle
- Contractile Properties of Human Skeletal Muscle: Normal and Thyroid Disease
- Creators
- Masaharu TakamoriLudwig GutmannStanley R Shane
- Resource Type
- Journal article
- Publication Details
- Archives of neurology (Chicago), Vol.25(6), pp.535-546
- DOI
- 10.1001/archneur.1971.00490060069007
- PMID
- 5115554
- NLM abbreviation
- Arch Neurol
- ISSN
- 0003-9942
- eISSN
- 1538-3687
- Publisher
- American Medical Association
- Language
- English
- Date published
- 12/01/1971
- Academic Unit
- Neurology
- Record Identifier
- 9984020652202771
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