Journal article
Controversies in tuberculous infection among pediatric infectious disease specialists in North America
The international journal of tuberculosis and lung disease, Vol.20(11), pp.1463-1468
11/01/2016
DOI: 10.5588/ijtld.16.0366
PMID: 27776586
Abstract
OBJECTIVE: To evaluate the extent to which advancements in the diagnosis and treatment of latent tuberculous infection (LTBI) have been integrated into practice by pediatric infectious disease (PID) specialists.DESIGN: We conducted an online survey of the Infectious Diseases Society
of America's Emerging Infections Network (EIN) membership.RESULTS: Of the 323 members, 197 (61%) responded: 7% cared for 5 children with TB disease and 34% for 5 children with LTBI annually. We identified substantial variations in the use of interferon-gamma release assays (IGRAs)
based upon age, immune status, and TB risk factors. In addition, tuberculin skin test (TST) use was three times more common in younger children. Variations existed in managing children with discordant TST and IGRA results. Less variation existed in LTBI treatment, with 86% preferring a 9-month
course of isoniazid; few other, newer regimens were used routinely.CONCLUSION: Substantial variations exist in LTBI management; uptake of newer diagnostic tools and treatment regimens has been slow. Variations in practice and the lag time to integrating new data into practice may indicate
the relative infrequency with which providers encounter LTBI. Our findings reflect the need for increased visibility of existing TB guidelines and resources for expert consultation for scenarios not covered by guidelines.
Details
- Title: Subtitle
- Controversies in tuberculous infection among pediatric infectious disease specialists in North America
- Creators
- A. T Cruz - Baylor College of MedicineA. L Hersh - University of UtahJ. R Starke - Baylor College of MedicineS. E Beekmann - University of IowaP. M Polgreen - University of IowaR Banerjee - Mayo Clinic in Florida
- Resource Type
- Journal article
- Publication Details
- The international journal of tuberculosis and lung disease, Vol.20(11), pp.1463-1468
- DOI
- 10.5588/ijtld.16.0366
- PMID
- 27776586
- NLM abbreviation
- Int J Tuberc Lung Dis
- ISSN
- 1027-3719
- eISSN
- 1815-7920
- Publisher
- International Union Against Tuberculosis and Lung Disease
- Language
- English
- Date published
- 11/01/2016
- Academic Unit
- Infectious Diseases; Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984360041202771
Metrics
12 Record Views