Journal article
Cordova: web-based management of genetic variation data
Bioinformatics (Oxford, England), Vol.30(23), pp.3438-3439
12/01/2014
DOI: 10.1093/bioinformatics/btu539
PMCID: PMC4296146
PMID: 25123904
Abstract
Cordova is an out-of-the-box solution for building and maintaining an online database of genetic variations integrated with pathogenicity prediction results from popular algorithms. Our primary motivation for developing this system is to aid researchers and clinician-scientists in determining the clinical significance of genetic variations. To achieve this goal, Cordova provides an interface to review and manually or computationally curate genetic variation data as well as share it for clinical diagnostics and the advancement of research. Cordova is open source under the MIT license and is freely available for download at https://github.com/clcg/cordova.
Details
- Title: Subtitle
- Cordova: web-based management of genetic variation data
- Creators
- Sean S Ephraim - University of IowaNikhil Anand - University of IowaAdam P DeLuca - University of IowaKyle R Taylor - University of IowaDiana L Kolbe - University of IowaAllen C Simpson - University of IowaHela Azaiez - University of IowaChristina M Sloan - University of IowaA Eliot Shearer - University of IowaAndrea R Hallier - University of IowaThomas L Casavant - University of IowaTodd E Scheetz - University of IowaRichard J H Smith - University of IowaTerry A Braun - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Bioinformatics (Oxford, England), Vol.30(23), pp.3438-3439
- DOI
- 10.1093/bioinformatics/btu539
- PMID
- 25123904
- PMCID
- PMC4296146
- NLM abbreviation
- Bioinformatics
- ISSN
- 1460-2059
- eISSN
- 1367-4811
- Publisher
- England
- Grant note
- DC002842 / NIDCD NIH HHS R01 DC003544 / NIDCD NIH HHS GM082729 / NIGMS NIH HHS DC011674 / NIDCD NIH HHS T32 GM007337 / NIGMS NIH HHS DC012049 / NIDCD NIH HHS DC003544 / NIDCD NIH HHS
- Language
- English
- Date published
- 12/01/2014
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Molecular Physiology and Biophysics; Anatomy and Cell Biology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Center for Bioinformatics and Computational Biology; Otolaryngology; Internal Medicine; Ophthalmology and Visual Sciences; Iowa Institute of Human Genetics
- Record Identifier
- 9983979988902771
Metrics
25 Record Views