Journal article
Coronary-Artery Vasoconstriction Induced by Cocaine, Cigarette Smoking, or Both
The New England journal of medicine, Vol.330(7), pp.454-459
02/17/1994
DOI: 10.1056/NEJM199402173300702
PMID: 8289850
Abstract
Over the past decade, cocaine abuse has become widespread, with over 30 million Americans estimated to have used it
1
. As its use has escalated, cocaine-associated catastrophic cardiac events, such as acute myocardial infarction and sudden death, have been reported occasionally. Although even small amounts of intranasal cocaine increase the metabolic requirement of the heart for oxygen and decrease the supply of oxygen,
2
the mechanisms whereby cocaine abuse sometimes causes cardiac catastrophes are poorly understood.
Previous studies have shown that cigarette smoking also causes a slight increase in myocardial oxygen demand and a concomitant reduction in supply
3
–
8
. Other . . .
Details
- Title: Subtitle
- Coronary-Artery Vasoconstriction Induced by Cocaine, Cigarette Smoking, or Both
- Creators
- David J MoliternoJohn E WillardRichard A LangeBrian H NegusJames D BoehrerD. Brent GlamannCharles LandauJames D RossenMichael D WinnifordL. David Hillis
- Resource Type
- Journal article
- Publication Details
- The New England journal of medicine, Vol.330(7), pp.454-459
- DOI
- 10.1056/NEJM199402173300702
- PMID
- 8289850
- NLM abbreviation
- N Engl J Med
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- Publisher
- Massachusetts Medical Society
- Language
- English
- Date published
- 02/17/1994
- Academic Unit
- Neurology; Cardiovascular Medicine; Neurosurgery; Internal Medicine
- Record Identifier
- 9984020780902771
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