Journal article
Correlation Between in Vitro Studies and Response to Antibiotic Therapy in Staphylococcic Bacteremia
A.M.A. archives of internal medicine, Vol.104(2), pp.226-233
08/01/1959
DOI: 10.1001/archinte.1959.00270080052006
PMID: 13669776
Abstract
The selection of the proper antibiotic is a major problem that faces the clinician who makes the diagnosis of Staphylococcus pyogenes var. aureus bacteremia. The present study was done to determine how helpful the tube-dilution method of determining bacterial sensitivity to antibiotics was in solving this problem.In vitro antibiotic sensitivity tests have been criticized as inadequate because of the different milieu in which the antibiotic must act in vivo.1,2 Despite this criticism, many physicians are greatly influenced by the results of commercial disk antibiotic-sensitivity tests that are used in most bacteriology laboratories.3,4 Previous reports have stressed the lack of standardization of the disk method in testing antibiotic sensitivity of bacterial strains, and there was striking variability in the results reported from different laboratories.5-8 "False resistance" in many tests has been related to the rates of diffusion and deterioration of the antibiotic and has deprived patients of
Details
- Title: Subtitle
- Correlation Between in Vitro Studies and Response to Antibiotic Therapy in Staphylococcic Bacteremia
- Creators
- FRANÇOIS M ABBOUDBURTON A WAISBREN
- Resource Type
- Journal article
- Publication Details
- A.M.A. archives of internal medicine, Vol.104(2), pp.226-233
- DOI
- 10.1001/archinte.1959.00270080052006
- PMID
- 13669776
- NLM abbreviation
- AMA Arch Intern Med
- ISSN
- 0888-2479
- eISSN
- 2375-6799
- Publisher
- American Medical Association
- Language
- English
- Date published
- 08/01/1959
- Academic Unit
- Molecular Physiology and Biophysics; Cardiovascular Medicine; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
- Record Identifier
- 9984025331902771
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