Journal article
Correlation between extraversion and regional cerebral blood flow in response to olfactory stimuli
The American journal of psychiatry, Vol.164(2), pp.339-341
02/2007
DOI: 10.1176/appi.ajp.164.2.339
PMID: 17267799
Abstract
Extraversion, a trait associated with individual differences in approach motivation and the experience of positive emotional states, is negatively correlated with certain psychiatric disorders, including depression and social phobia. The authors examined the correlation between extraversion and regional cerebral blood flow (rCBF) while participants were exposed to olfactory stimuli in order to further characterize individual differences in hedonic processing associated with this trait.
Twelve healthy participants were exposed to pleasant and unpleasant odors while rCBF was measured using [(15)O] water PET. The NEO Five-Factor Inventory was used to assess extraversion. Associations between extraversion scores and rCBF in each olfactory stimulus condition were assessed by correlational analysis.
During the pleasant smell condition, extraversion was correlated with rCBF in the amygdala and occipital cortex. During the unpleasant smell condition, extraversion was correlated with rCBF in the occipital cortex and inferior temporal gyrus.
These results provide important evidence for the biological basis of extraversion and indicate that there are systematic individual differences in patterns of brain activation in response to affective stimuli.
Details
- Title: Subtitle
- Correlation between extraversion and regional cerebral blood flow in response to olfactory stimuli
- Creators
- Jatin G Vaidya - W278 GH, Department of Psychiatry, University of Iowa, 200 Hawkins Dr., Iowa City, IA 52242, USA. jatin-vaidya@uiowa.eduSergio ParadisoNancy C AndreasenDebra L JohnsonLaura L Boles PontoRichard D Hichwa
- Resource Type
- Journal article
- Publication Details
- The American journal of psychiatry, Vol.164(2), pp.339-341
- Publisher
- United States
- DOI
- 10.1176/appi.ajp.164.2.339
- PMID
- 17267799
- ISSN
- 0002-953X
- eISSN
- 1535-7228
- Grant note
- T32 MH-19113 / NIMH NIH HHS
- Language
- English
- Date published
- 02/2007
- Academic Unit
- Radiology; Psychiatry; Research Administration; Psychological and Brain Sciences; Iowa Neuroscience Institute; Pharmaceutical Sciences and Experimental Therapeutics; Physics and Astronomy; Radiation Oncology; University College Courses
- Record Identifier
- 9984003480502771
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