Journal article
Correlation between preoperative endoscopic ultrasound and surgical pathology staging of gastric adenocarcinoma: A single institution retrospective review
Journal of surgical oncology, Vol.113(1), pp.42-45
01/01/2016
DOI: 10.1002/jso.24098
PMID: 26784562
Abstract
BackgroundRecent evidence validates the effectiveness of neoadjuvant chemotherapy in the treatment of gastric adenocarcinoma. Endoscopic ultrasonographic (EUS) staging has been proposed as a useful adjunct in this setting.
MethodsWe performed a retrospective review of patients treated at our institution for gastric adenocarcinoma between July 2005 and January 2014. We identified patients referred for EUS before surgery as part of a prospective treatment plan. Histopathologic staging was compared to EUS staging, with a focus on T- and N-stage. Agreement between the two modalities was examined using kappa-statistics.
ResultsWe identified 614 patients with biopsy-proven gastric adenocarcinoma; 145 underwent curative-intent surgery. Surgical pathology and EUS results were available from 69 patients. The accuracy of EUS for the evaluation of T- and N-stage was 44.9% and 56.5%, respectively. EUS demonstrated greater concordance with histopathology at evaluating T-stage (=0.3469) than N-stage (=0.1316). EUS underestimated T- and N-stage in 40.8% and 30.4% of patients, respectively.
ConclusionEUS seems to correlate poorly with pathology in the preoperative staging of gastric adenocarcinoma. In the majority of inaccurate cases, EUS underestimates T-stage and N-stage, limiting its utility in the neoadjuvant setting. J. Surg. Oncol. 2016;113:42-45. (c) 2016 Wiley Periodicals, Inc.
Details
- Title: Subtitle
- Correlation between preoperative endoscopic ultrasound and surgical pathology staging of gastric adenocarcinoma: A single institution retrospective review
- Creators
- Oscar K. Serrano - Yeshiva UniversityKevin Huang - Albert Einstein College of MedicineNicole Ng - Albert Einstein College of MedicineJulie Yang - Yeshiva UniversityPatricia Friedmann - Albert Einstein College of MedicineSteven K. Libutti - Yeshiva UniversityTimothy J. Kennedy - Yeshiva University
- Resource Type
- Journal article
- Publication Details
- Journal of surgical oncology, Vol.113(1), pp.42-45
- Publisher
- Wiley
- DOI
- 10.1002/jso.24098
- PMID
- 26784562
- ISSN
- 0022-4790
- eISSN
- 1096-9098
- Number of pages
- 4
- Language
- English
- Date published
- 01/01/2016
- Academic Unit
- Surgery
- Record Identifier
- 9984322792002771
Metrics
7 Record Views