Journal article
Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene: evidence for assortative mating
Behavioral and brain functions, Vol.7(1), pp.45-45
10/18/2011
DOI: 10.1186/1744-9081-7-45
PMCID: PMC3219594
PMID: 22008211
Abstract
Triplet repeats contribute to normal variation in behavioral traits and when expanded, cause brain disorders. While Huntington's Disease is known to be caused by a CAG triplet repeat in the gene Huntingtin, the effect of CAG repeats on brain function below disease threshold has not been studied. The current study shows a significant correlation between the CAG repeat length of the maternal and paternal allele in the Huntingtin gene among healthy subjects, suggesting assortative mating.
Details
- Title: Subtitle
- Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene: evidence for assortative mating
- Creators
- Peg Nopoulos - Department of Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USAEric A Epping - Department of Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USATom Wassink - Department of Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USABradley L Schlaggar - Department of Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USAJoel Perlmutter - Department of Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA
- Resource Type
- Journal article
- Publication Details
- Behavioral and brain functions, Vol.7(1), pp.45-45
- DOI
- 10.1186/1744-9081-7-45
- PMID
- 22008211
- PMCID
- PMC3219594
- NLM abbreviation
- Behav Brain Funct
- ISSN
- 1744-9081
- eISSN
- 1744-9081
- Publisher
- BioMed Central
- Language
- English
- Date published
- 10/18/2011
- Academic Unit
- Neurology; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984003415002771
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