Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents

Eric B Emmons; Rafael N Ruggiero; Ryan M Kelley; Krystal L Parker; Nandakumar S Narayanan

doi:10.3389/fpsyg.2016.00459

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Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents

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Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents

Eric B Emmons, Rafael N Ruggiero, Ryan M Kelley, Krystal L Parker and Nandakumar S Narayanan

Frontiers in psychology, Vol.7, pp.459-459

2016

DOI: 10.3389/fpsyg.2016.00459

PMCID: PMC4820903

PMID: 27092091

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Abstract

Organizing movements in time is a critical and highly conserved feature of mammalian behavior. Temporal control of action requires corticostriatal networks. We investigate these networks in rodents using a two-interval timing task while recording LFPs in medial frontal cortex (MFC) or dorsomedial striatum. Consistent with prior work, we found cue-triggered delta (1–4 Hz) and theta activity (4–8 Hz) primarily in rodent MFC. We observed delta activity across temporal intervals in MFC and dorsomedial striatum. Rewarded responses were associated with increased delta activity in MFC. Activity in theta bands in MFC and delta bands in the striatum was linked with the timing of responses. These data suggest both delta and theta activity in frontostriatal networks are modulated during interval timing and that activity in these bands may be involved in the temporal control of action.

local field potential

striatum

medial frontal cortex

Psychology

prefrontal cortex

dorsomedial striatum

temporal control

interval timing

Parkinson’s disease

Details

Title: Subtitle: Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents
Creators: Eric B Emmons - Department of Neurology, Carver College of Medicine, The University of Iowa
Rafael N Ruggiero - Department of Neuroscience and Behavioral Sciences, University of São Paulo
Ryan M Kelley - Department of Neurology, Carver College of Medicine, The University of Iowa
Krystal L Parker - Department of Neurology, Carver College of Medicine, The University of Iowa
Nandakumar S Narayanan - Aging Mind and Brain Initiative, Carver College of Medicine, The University of Iowa
Resource Type: Journal article
Publication Details: Frontiers in psychology, Vol.7, pp.459-459
DOI: 10.3389/fpsyg.2016.00459
PMID: 27092091
PMCID: PMC4820903
NLM abbreviation: Front Psychol
ISSN: 1664-1078
eISSN: 1664-1078
Publisher: Frontiers Media S.A
Grant note: 2014/22817-1 / Fundação de Amparo à Pesquisa do Estado de São Paulo K08 / National Institutes of Health R01 / National Institutes of Health
Language: English
Date published: 2016
Academic Unit: Neurology; Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute
Record Identifier: 9984003454102771

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