Journal article
Cost-utility analysis of an integrated genetic/epigenetic test for assessing risk for coronary heart disease
Epigenomics, Vol.13(7), pp.531-547
04/2021
DOI: 10.2217/epi-2021-0021
PMID: 33625255
Abstract
New epigenetically based methods for assessing risk for coronary heart disease may be more sensitive but are generally more costly than current methods. To understand their potential impact on healthcare spending, we conducted a cost-utility analysis.
We compared costs using the new Epi + Gen CHD™ test with those of existing tests using a cohort Markov simulation model.
We found that use of the new test was associated with both better survival and highly competitive negative incremental cost-effectiveness ratios ranging from -$42,000 to -$8000 per quality-adjusted life year for models with and without a secondary test.
The new integrated genetic/epigenetic test will save money and lives under most real-world scenarios. Similar advantages may be seen for other epigenetic tests.
Details
- Title: Subtitle
- Cost-utility analysis of an integrated genetic/epigenetic test for assessing risk for coronary heart disease
- Creators
- Younsoo Jung - Cardio Diagnostics Inc., Coralville, IA 52241, USADavid Frisvold - Department of Economics, University of Iowa, Iowa City, IA 52242, USATimur Dogan - Cardio Diagnostics Inc., Coralville, IA 52241, USAMeeshanthini Dogan - Cardio Diagnostics Inc., Coralville, IA 52241, USARob Philibert - Department of Psychiatry, University of Iowa, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Epigenomics, Vol.13(7), pp.531-547
- Publisher
- England
- DOI
- 10.2217/epi-2021-0021
- PMID
- 33625255
- ISSN
- 1750-1911
- eISSN
- 1750-192X
- Language
- English
- Date published
- 04/2021
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Psychiatry; Economics; Iowa Neuroscience Institute; Public Policy Center (Archive)
- Record Identifier
- 9984070993302771
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