Counterpoint: Low-Density Lipoprotein Cholesterol Targets Are Not Needed in Lipid Treatment Guidelines

Jennifer G Robinson; Kausik Ray

doi:10.1161/ATVBAHA.116.306887

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Counterpoint: Low-Density Lipoprotein Cholesterol Targets Are Not Needed in Lipid Treatment Guidelines

Journal article

Open access

Peer reviewed

Counterpoint: Low-Density Lipoprotein Cholesterol Targets Are Not Needed in Lipid Treatment Guidelines

Jennifer G Robinson and Kausik Ray

Arteriosclerosis, thrombosis, and vascular biology, Vol.36(4), pp.586-590

04/2016

DOI: 10.1161/ATVBAHA.116.306887

PMID: 26988588

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https://doi.org/10.1161/ATVBAHA.116.306887View

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Abstract

On the basis of accumulating evidence, low-density lipoprotein cholesterol (LDL-C) treat-to-goal approaches no longer seem to be the best way to optimize lipid-modifying therapy to prevent atherosclerotic cardiovascular disease (ASCVD). The potential for a net ASCVD risk reduction benefit is a more individualized approach to clinical decision making and may better inform patient preferences. However, risk estimation tools will need to be developed to facilitate more personalized CVD risk estimation in statin-treated patients. In the meantime, LDL-C thresholds rather than targets may aid in determining which patients might benefit from additional LDL-C-lowering therapy beyond statins.

Cardiovascular Diseases - etiology

Predictive Value of Tests

Dyslipidemias - drug therapy

Dyslipidemias - complications

Risk Assessment

Cardiovascular Diseases - prevention & control

Humans

Risk Factors

Decision Support Techniques

Treatment Outcome

Biomarkers - blood

Patient Selection

Dyslipidemias - blood

Anticholesteremic Agents - therapeutic use

Cardiovascular Diseases - blood

Cholesterol, LDL - blood

Drug Therapy, Combination

Dyslipidemias - diagnosis

Cardiovascular Diseases - diagnosis

Practice Guidelines as Topic

Details

Title: Subtitle: Counterpoint: Low-Density Lipoprotein Cholesterol Targets Are Not Needed in Lipid Treatment Guidelines
Creators: Jennifer G Robinson - University of Iowa, Epidemiology
Kausik Ray - Imperial College London
Resource Type: Journal article
Publication Details: Arteriosclerosis, thrombosis, and vascular biology, Vol.36(4), pp.586-590
Publisher: United States
DOI: 10.1161/ATVBAHA.116.306887
PMID: 26988588
ISSN: 1079-5642
eISSN: 1524-4636
Language: English
Date published: 04/2016
Academic Unit: Epidemiology; Internal Medicine
Record Identifier: 9983995005502771

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