Journal article
Course and Outcome of Children with Convulsive Status Epilepticus Admitted to a Pediatric Intensive Care Unit
Curēus (Palo Alto, CA), Vol.11(4), pp.e4471-e4471
04/16/2019
DOI: 10.7759/cureus.4471
PMCID: PMC6579347
PMID: 31249749
Abstract
Introduction
The objective of this study was to describe the course and the outcomes of children with convulsive status epilepticus and to evaluate the differences between two groups of children with new-onset seizures and known seizure disorders.
Methods
This is a retrospective, single-center study. Children with convulsive status epilepticus admitted to our tertiary care pediatric intensive care unit were included in the study. Medical records were reviewed to obtain the demographic- and seizure-related variables.
Results
Among 139 children with status epilepticus, 69.7% (
n
= 99) had a known seizure disorder. Focal seizures were present in 23.9% of children, and 34.6% required intubation; there was an overall mortality rate of 1.2%. The children with new-onset seizures were younger and received electroencephalography (EEG) and neuroimaging more often compared to children with known seizure disorders (
p
< 0.05). However, an abnormal EEG was more common among children with known seizure disorders (
p
< 0.001).
Conclusions
Sub-therapeutic anti-epileptic drugs levels were common among children with known seizure disorders presenting with status epilepticus. Gender, race, insurance status, type of seizures, intubation requirement, lengths of stay, and mortality were not significantly different between the two groups.
Details
- Title: Subtitle
- Course and Outcome of Children with Convulsive Status Epilepticus Admitted to a Pediatric Intensive Care Unit
- Creators
- Madhuradhar Chegondi - University of IowaMary M Garland - Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa, USA Surgery, Herbert Wertheim College of Medicine, Miami, USA Pediatrics, Nicklaus Children’s Hospital, Miami, USAPrithvi Sendi - University of IowaAnuj R Jayakar - Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa, USA Surgery, Herbert Wertheim College of Medicine, Miami, USA Pediatrics, Nicklaus Children’s Hospital, Miami, USABalagangadhar R Totapally - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Curēus (Palo Alto, CA), Vol.11(4), pp.e4471-e4471
- DOI
- 10.7759/cureus.4471
- PMID
- 31249749
- PMCID
- PMC6579347
- NLM abbreviation
- Cureus
- ISSN
- 2168-8184
- eISSN
- 2168-8184
- Publisher
- Cureus
- Language
- English
- Date published
- 04/16/2019
- Academic Unit
- Stead Family Department of Pediatrics
- Record Identifier
- 9984354522602771
Metrics
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