Coxiella burnetii vascular graft infection

Takaaki Kobayashi; Fernando Casado Castillo; Jason H. Barker; Loreen Herwaldt

doi:10.1016/j.idcr.2021.e01230

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Coxiella burnetii vascular graft infection

Journal article

Open access

Peer reviewed

Coxiella burnetii vascular graft infection

Takaaki Kobayashi, Fernando Casado Castillo, Jason H. Barker and Loreen Herwaldt

IDCases, Vol.25, p.e01230

01/01/2021

DOI: 10.1016/j.idcr.2021.e01230

PMCID: PMC8335630

PMID: 34381690

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https://doi.org/10.1016/j.idcr.2021.e01230View

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Abstract

Q fever, a zoonotic infection caused by Coxiella burnetii, can present with a wide spectrum of clinical manifestations. The organism is typically transmitted from sheep, goats, or cattle to humans via contaminated aerosols. On average, 1-5% of patients with acute Q fever will develop chronic infection months to decades after their primary infections. We report a case of a chronic vascular graft infection due to Coxiella burnetii in a 61-year-old man without direct exposure to animals who presented with recurrent fever. Indium-111-labeled white blood cell scan with single-emission positron computed tomography demonstrated findings suggesting a graft infection. C. burnetii phase I and phase II IgG antibody titers were > 1:32,768 and polymerase chain reaction performed on the explanted graft was positive for C burnetii. Q fever should be considered in the differential diagnosis of vascular infections in patients who have a pre-existing lesion such as an aneurysm, or vascular prosthesis even in the absence of a history of direct animal exposure. (C) 2021 The Authors. Published by Elsevier Ltd.

Infectious Diseases

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: Coxiella burnetii vascular graft infection
Creators: Takaaki Kobayashi - University of Iowa Hospitals and Clinics
Fernando Casado Castillo - University of Iowa Hospitals and Clinics
Jason H. Barker - University of Iowa Hospitals and Clinics
Loreen Herwaldt - University of Iowa Hospitals and Clinics
Resource Type: Journal article
Publication Details: IDCases, Vol.25, p.e01230
DOI: 10.1016/j.idcr.2021.e01230
PMID: 34381690
PMCID: PMC8335630
NLM abbreviation: IDCases
ISSN: 2214-2509
eISSN: 2214-2509
Publisher: Elsevier
Number of pages: 4
Language: English
Date published: 01/01/2021
Academic Unit: Infectious Diseases; Epidemiology; Internal Medicine
Record Identifier: 9984360045302771

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