Crossed Cerebellar Diaschisis in Status Epilepticus

Edgar Samaniego; Erika Stuckert; Nancy Fischbein; Christine Wijman

doi:10.1007/s12028-009-9312-y

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Crossed Cerebellar Diaschisis in Status Epilepticus

Journal article

Peer reviewed

Crossed Cerebellar Diaschisis in Status Epilepticus

Edgar Samaniego, Erika Stuckert, Nancy Fischbein and Christine Wijman

Neurocritical care, Vol.12(1), pp.88-90

02/2010

DOI: 10.1007/s12028-009-9312-y

PMID: 19967565

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Abstract

Crossed cerebellar diaschisis (CCD) has been reported on positron-emission tomography and single-photon emission computed tomography of stroke patients. Rarely it has been described with brain diffusion-weighted MRI (DWI) of status epilepticus (SE).Case report.A 53-year-old woman was found unresponsive after cocaine use. A diagnostic electroencephalogram was consistent with ictal SE. A brain DWI showed reduced diffusion in the left temporo-parietal and occipital cortexes, the left thalamus and the right cerebellum. The DWI changes did not correspond to a vascular territory and were attributed to seizure activity and secondary CCD. A 2-week follow-up DWI showed interval near-complete resolution of the diffusion changes. CCD in SE may represent injury caused by excessive neuronal transmission from prolonged excitatory synaptic activity via the cortico-pontine-cerebellar pathway. Alternatively, it may be a result of interruption of the cortico-pontine-cerebellar pathway with loss of cortical inhibitory input.This case documents CCD during SE, providing further evidence of contralateral cerebellar involvement with a supratentorial epileptiform focus.

Cerebellum

Neurology

Internal Medicine

Medicine & Public Health

Crossed cerebellar diaschisis

DWI

Status epilepticus

Details

Title: Subtitle: Crossed Cerebellar Diaschisis in Status Epilepticus
Creators: Edgar Samaniego - Stanford University 701 Welch Road, Suite B 325 Palo Alto CA 94304 USA
Erika Stuckert - Stanford University 701 Welch Road, Suite B 325 Palo Alto CA 94304 USA
Nancy Fischbein - Stanford University 701 Welch Road, Suite B 325 Palo Alto CA 94304 USA
Christine Wijman - Stanford University 701 Welch Road, Suite B 325 Palo Alto CA 94304 USA
Resource Type: Journal article
Publication Details: Neurocritical care, Vol.12(1), pp.88-90
DOI: 10.1007/s12028-009-9312-y
PMID: 19967565
NLM abbreviation: Neurocrit Care
ISSN: 1541-6933
eISSN: 1556-0961
Publisher: Humana Press Inc; New York
Language: English
Date published: 02/2010
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984020653602771

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