Journal article
Cryoablation Therapy for Atrioventricular Nodal Reentrant Tachycardia in Children: A Multicenter Experience of Efficacy
Pediatric cardiology, Vol.33(7), pp.1147-1153
10/2012
DOI: 10.1007/s00246-012-0273-0
PMID: 22430375
Abstract
Atrioventricular nodal reentrant tachycardia (AVNRT), a common tachycardia in children, is routinely treated by catheter ablation using radiofrequency or cryothermal energy. Acute success rates of 95–97 % are reported for cryoablation, similar to those achieved with radiofrequency ablation (RFA). However, early studies reported higher recurrence rates after cryoablation for treatment of AVNRT than those reported for RFA. This study evaluated the success and recurrence rates for cryoablation in a current cohort of pediatric patients across several institutions. Patients 21 years old or younger with AVNRT who underwent cryoablation at five participating centers between 2004 and 2009 were retrospectively reviewed. Patient demographics and procedural data were extracted from patient records and analyzed. A total of 434 patients with AVNRT who underwent cryoablation were identified. Cryoablation was used as the exclusive ablation method for 379 patients. For 97 % (368/379) of these patients, cryoablation was acutely successful. A higher acute success rate was found with the 6-mm-tip catheter (99 %) than with the 4-mm-tip catheter (91 %) (p < 0.01). Recurrence was experienced by 7.3 % of the patients. Recurrence was more likely for those treated with the 4-mm-tip catheter (6/42, 14 %) than for those who had the larger catheters (12/204, 6 %) No patient experienced permanent heart block. Success and recurrence rates for this cohort of patients were similar to those reported for RFA used to treat AVNRT in pediatric patients. The findings show a higher success rate and a lower recurrence rate after cryoablation with a 6-mm-tip catheter than after use of the 4-mm-tip catheter, with an associated excellent safety profile.
Details
- Title: Subtitle
- Cryoablation Therapy for Atrioventricular Nodal Reentrant Tachycardia in Children: A Multicenter Experience of Efficacy
- Creators
- Srikant Das - Sibley Heart Center, Children’s Healthcare of Atlanta Emory University 2835 Brandywine Road, Ste. 300 Atlanta GA 30341 USAIan Law - Department of Pediatric Cardiology, Children’s Heart Center University of Nevada Las Vegas NV USANicholas Von Bergen - Department of Pediatric Cardiology, Children’s Heart Center University of Nevada Las Vegas NV USADavid Bradley - Department of Pediatric Cardiology The University of Michigan Ann Arbor MI USAMacdonald Dick II - Department of Pediatric Cardiology The University of Michigan Ann Arbor MI USASusan Etheridge - Department of Pediatric Cardiology, Primary Children’s Medical Center, School of Medicine The University of Utah Salt Lake UT USAElizabeth Saarel - Department of Pediatric Cardiology, Primary Children’s Medical Center, School of Medicine The University of Utah Salt Lake UT USAPatricio Frias - Sibley Heart Center, Children’s Healthcare of Atlanta Emory University 2835 Brandywine Road, Ste. 300 Atlanta GA 30341 USAMargaret Strieper - Sibley Heart Center, Children’s Healthcare of Atlanta Emory University 2835 Brandywine Road, Ste. 300 Atlanta GA 30341 USAPeter Fischbach - Sibley Heart Center, Children’s Healthcare of Atlanta Emory University 2835 Brandywine Road, Ste. 300 Atlanta GA 30341 USA
- Resource Type
- Journal article
- Publication Details
- Pediatric cardiology, Vol.33(7), pp.1147-1153
- Publisher
- Springer-Verlag
- DOI
- 10.1007/s00246-012-0273-0
- PMID
- 22430375
- ISSN
- 0172-0643
- eISSN
- 1432-1971
- Language
- English
- Date published
- 10/2012
- Academic Unit
- Cardiology; Stead Family Department of Pediatrics
- Record Identifier
- 9984093226602771
Metrics
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