Current Advances in Endovascular Treatment of Intracranial Atherosclerotic Disease and Future Prospective

Mostafa Jafari; Thanh N. Nguyen; Santiago Ortega-Gutierrez; Muhammad Shazam Hussain; Ameer E. Hassan; Asad Ikram; Javed Khader Eliyas; Gustavo J. Rodriguez; Afshin A. Divani

doi:10.1016/j.jstrokecerebrovasdis.2020.105556

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Current Advances in Endovascular Treatment of Intracranial Atherosclerotic Disease and Future Prospective

Journal article

Peer reviewed

Current Advances in Endovascular Treatment of Intracranial Atherosclerotic Disease and Future Prospective

Mostafa Jafari, Thanh N. Nguyen, Santiago Ortega-Gutierrez, Muhammad Shazam Hussain, Ameer E. Hassan, Asad Ikram, Javed Khader Eliyas, Gustavo J. Rodriguez and Afshin A. Divani

Journal of stroke and cerebrovascular diseases, Vol.30(3), pp.105556-105556

03/01/2021

DOI: 10.1016/j.jstrokecerebrovasdis.2020.105556

PMID: 33360252

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Abstract

Objectives/Background: Medical therapy is the first line of treatment for intracranial atherosclerotic disease (ICAD). Percutaneous transluminal angioplasty and stenting (PTAS) are mainly considered for those patients with severe stenosis and recurrent events despite aggressive medical therapy. In this review, we discuss the application of PTAS as a treatment option for ICAD and its future prospect. Materials and Methods: We did the literature review of the key articles and guidelines to elaborate on the role of PTAS in the management of ICAD based on the current data and expert opinion. We searched PubMed, Google Scholar, and Scopus up to August 2020, and included articles published only in the English language. Results: Since the publication of the results from SAMMPRIS and VISSIT trials, stenting is no longer recommended for secondary stroke prevention in patients with symptomatic ICAD. However, recent clinical studies on intracranial stenting for a subgroup of ICAD patients have shown promising results, likely due to better patient selection and continued advancement of endovascular techniques. Conclusion: There exists a lack of consensus regarding the best endovascular treatment approach (e.g., angioplasty alone or balloon mounted stent vs. self-expanding stent with or without prior angioplasty) or management of in-stent restenosis. Another area of clinical controversy relates to the ideal use and duration of antiplatelet therapy.

Cardiovascular System & Cardiology

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

Peripheral Vascular Disease

Science & Technology

Details

Title: Subtitle: Current Advances in Endovascular Treatment of Intracranial Atherosclerotic Disease and Future Prospective
Creators: Mostafa Jafari - Baylor College of Medicine
Thanh N. Nguyen - Boston University
Santiago Ortega-Gutierrez - University of Iowa
Muhammad Shazam Hussain - Cleveland Clinic
Ameer E. Hassan - Departments of Neurology and Radiology, University of Texas Health Science Center - San Antonio, TX, United States; Department of Neurology, University of Texas Rio Grande Valley, Valley Baptist Neuroscience Institute, Harlingen, TX, United States.
Asad Ikram - University of New Mexico
Javed Khader Eliyas - University of New Mexico
Gustavo J. Rodriguez - Texas Tech University Health Sciences Center at El Paso
Afshin A. Divani - University of New Mexico
Resource Type: Journal article
Publication Details: Journal of stroke and cerebrovascular diseases, Vol.30(3), pp.105556-105556
DOI: 10.1016/j.jstrokecerebrovasdis.2020.105556
PMID: 33360252
NLM abbreviation: J Stroke Cerebrovasc Dis
ISSN: 1052-3057
eISSN: 1532-8511
Publisher: Elsevier Inc
Number of pages: 13
Language: English
Date published: 03/01/2021
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984302203302771

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