Cushing's syndrome

Amal Shibli-Rahhal; Marta Van Beek; Janet A Schlechte

doi:10.1016/j.clindermatol.2006.04.012

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Journal article

Peer reviewed

Cushing's syndrome

Amal Shibli-Rahhal, Marta Van Beek and Janet A Schlechte

Clinics in dermatology, Vol.24(4), pp.260-265

07/2006

DOI: 10.1016/j.clindermatol.2006.04.012

PMID: 16828407

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Abstract

Cushing's syndrome results from prolonged exposure to excess glucocorticoids. Patients with Cushing's syndrome may develop multiple metabolic problems including obesity, hyperglycemia, hypertension, depression, low bone mass, muscle atrophy, and hypogonadism. Cutaneous manifestations of hypercortisolism include skin atrophy, excessive bruising, purple striations, poor wound healing, facial plethora, vellous hypertrichosis and hirsutism. Diagnostic tests used to screen for Cushing's syndrome include 24-hour urine cortisol, the 1 mg dexamethasone suppresion test, and late night salivary cortisol. A normal screening test excludes the diagnosis of Cushing's. Patients with an abnormal screening test should be referred to an endocrinologist for complete evaluation of the pituitary-adrenal axis.

Cushing Syndrome - etiology

Skin - physiopathology

Cushing Syndrome - pathology

Cushing Syndrome - metabolism

Humans

Cushing Syndrome - diagnosis

Details

Title: Subtitle: Cushing's syndrome
Creators: Amal Shibli-Rahhal - Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
Marta Van Beek
Janet A Schlechte
Resource Type: Journal article
Publication Details: Clinics in dermatology, Vol.24(4), pp.260-265
Publisher: United States
DOI: 10.1016/j.clindermatol.2006.04.012
PMID: 16828407
ISSN: 0738-081X
eISSN: 1879-1131
Language: English
Date published: 07/2006
Academic Unit: Dermatology; Medicine Administration; Internal Medicine
Record Identifier: 9984001142302771

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