Journal article
Cutaneous actinomycoses leading to brain invasion: A case report
Asian Pacific journal of tropical medicine, Vol.18(9), pp.421-424
09/2025
DOI: 10.4103/apjtm.apjtm_305_25
Abstract
Rationale:
Central nervous system (CNS) actinomycosis is rare, spreading hematogenously from distant infections. Cutaneous actinomycosis with skull/meninges spread is especially unusual.
Patient concerns:
A 57-year-old man presented with complaints of discharge from the back of his scalp for six months, an ataxic gait, and bilateral upper and lower limb weakness and numbness over the past 4-5 months.
Diagnosis:
CNS actinomycosis.
Interventions:
Intravenous injection of ceftriaxone followed by oral amoxicillin-clavulanic acid therapy.
Outcomes:
The patient was able to walk without support, with complete resolution of sinus discharge.
Lessons:
In patients presenting with discharging sinuses especially when accompanied by CNS symptoms, actinomycosis should be considered as a differential, along with tuberculosis, non-tubercular mycobacterial infection, and aspergillosis. Microbiological confirmation should be attempted wherever possible, for accurate diagnosis and treatment, as clinic-radiological picture alone may not differentiate these infections, as treatment of each is diametrically opposite and patients can be cured with timely and appropriate treatment.
Details
- Title: Subtitle
- Cutaneous actinomycoses leading to brain invasion: A case report
- Creators
- Naman Lodha - All India Institute of Medical Sciences JodhpurAngirekula Shekhar - Department of General Medicine, AIIMS Jodhpur (Jodhpur City), IndiaNaresh Kumar Midha - All India Institute of Medical Sciences JodhpurAnanya Panda - Department of Radiology, University of Lowa, (Lowa City), USAKanishka Chaurasia - All India Institute of Medical Sciences JodhpurAnupama Bains - All India Institute of Medical Sciences JodhpurDeepak Kumar - Department of General Medicine, Division of Infectious Disease, AIIMS Jodhpur (Jodhpur City), India
- Resource Type
- Journal article
- Publication Details
- Asian Pacific journal of tropical medicine, Vol.18(9), pp.421-424
- DOI
- 10.4103/apjtm.apjtm_305_25
- ISSN
- 1995-7645
- eISSN
- 2352-4146
- Publisher
- WOLTERS KLUWER MEDKNOW PUBLICATIONS
- Number of pages
- 4
- Language
- English
- Date published
- 09/2025
- Academic Unit
- Radiology
- Record Identifier
- 9984969235702771
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