Cyclic AMP imaging sheds light on PDF signaling in circadian clock neurons

Seth M. Tomchik; Ronald L. Davis

doi:10.1016/j.neuron.2008.04.008

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Cyclic AMP imaging sheds light on PDF signaling in circadian clock neurons

Journal article

Open access

Peer reviewed

Cyclic AMP imaging sheds light on PDF signaling in circadian clock neurons

Seth M. Tomchik and Ronald L. Davis

Neuron (Cambridge, Mass.), Vol.58(2), pp.161-163

04/24/2008

DOI: 10.1016/j.neuron.2008.04.008

PMID: 18439399

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Abstract

In Drosophila, the neuropeptide PDF is required for circadian rhythmicity, but it is unclear where PDF acts. In this issue of Neuron, Shafer et al. use a novel bioimaging methodology to demonstrate that PDF elevates CAMP in nearly all clock neurons. Thus, PDF apparently exerts more widespread effects on the circadian clock network than suggested by previous studies of PDF receptor expression.

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

Science & Technology

Details

Title: Subtitle: Cyclic AMP imaging sheds light on PDF signaling in circadian clock neurons
Creators: Seth M. Tomchik - Baylor College of Medicine
Ronald L. Davis - Baylor College of Medicine
Resource Type: Journal article
Publication Details: Neuron (Cambridge, Mass.), Vol.58(2), pp.161-163
DOI: 10.1016/j.neuron.2008.04.008
PMID: 18439399
NLM abbreviation: Neuron
ISSN: 0896-6273
eISSN: 1097-4199
Publisher: Elsevier
Number of pages: 3
Language: English
Date published: 04/24/2008
Academic Unit: Iowa Neuroscience Institute; Neuroscience and Pharmacology
Record Identifier: 9984303742102771

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