Journal article
Cyclic Variation of Ultrasound Backscatter in Normal Myocardium Is View Dependent: Clinical Studies With a Real-Time Backscatter Imaging System
Journal of the American Society of Echocardiography, Vol.2(5), pp.308-314
09/1989
DOI: 10.1016/S0894-7317(89)80005-7
PMID: 2629869
Abstract
Real-time ultrasound backscatter imaging is a new method of evaluating relative integrated backscatter in a clinically applicable manner. The potential clinical utility of real-time backscatter imaging of diseased tissue depends on recognition of normal variations in cyclic backscatter when measured from different echocardiographic image orientations. The view dependence of cyclic backscatter variation was studied in normal human volunteers. In twenty normal male subjects (mean age 28 ± 5 years) cyclic variation in integrated backscatter (diastolic minus systolic backscatter) was assessed in multiple left ventricular regions with four standard two-dimensional echocardiographic views (parasternal long-axis and short-axis views, and apical two-chamber and four-chamber views). M-mode backscatter imaging was performed from the standard parasternal long-axis view. Cyclic variation in backscatter was present in the septum only when imaged from the parasternal long-axis view (2.7 ± 3.1 [standard deviation] decibels [dB], p < 0.01 for diastole versus systole). The posterior wall of the left ventricle demonstrated cyclic variation of integrated backscatter when imaged from both the parasternal long-axis (4.6 ± 1.6 dB, p < 0.01) and short-axis views (2.8 ± 2.2 dB, p < 0.01). Cyclic variation in integrated backscatter was not demonstrated in inferoseptal, septal, or lateral wall regions when imaged from the parasternal short-axis view. The apical views did not demonstrate cyclic variation in integrated backscatter in any of the segments studied. M-mode backscatter studies demonstrated cyclic variation in integrated backscatter in both the septal and posterior walls with both a “fixed” and “variable” region of interest at the chordal level of the left ventricle. At the papillary muscle level, however, only the posterior wall demonstrated cyclic variation in integrated backscatter. Thus both two-dimensional and M-mode real-time integrated backscatter imaging demonstrated cyclic variation in normal posterior and septal myocardium imaged with parasternal views but not with apical views, possibly because of angle dependence of ultrasound scattering. This normal view dependence of cyclic backscatter variation should be considered when interpreting regional alterations associated with disease states.
Details
- Title: Subtitle
- Cyclic Variation of Ultrasound Backscatter in Normal Myocardium Is View Dependent: Clinical Studies With a Real-Time Backscatter Imaging System
- Creators
- Byron F VandenbergLinda RathThomas A ShoupRichard E KerberSteve M CollinsDavid J Skorton
- Resource Type
- Journal article
- Publication Details
- Journal of the American Society of Echocardiography, Vol.2(5), pp.308-314
- Publisher
- Elsevier Inc
- DOI
- 10.1016/S0894-7317(89)80005-7
- PMID
- 2629869
- ISSN
- 0894-7317
- eISSN
- 1097-6795
- Language
- English
- Date published
- 09/1989
- Academic Unit
- Radiology; Electrical and Computer Engineering; Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984094756402771
Metrics
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