Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium

Journal article

Peer reviewed

Michael J Welsh, Alan E Smith, Joseph Zabner, Devra P Rich, Scott M Graham, Richard J Gregory, B M Pratt and Richard A Moscicki

Human gene therapy, Vol.5(2), pp.209-219

02/1994

DOI: 10.1089/hum.1994.5.2-209

PMID: 7514450

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Clinical protocol

Safety

Cystic Fibrosis - therapy

Membrane Proteins - genetics

Humans

Clinical Protocols

Adenoviruses, Human - physiology

Nasal Mucosa

Risk

Containment of Biohazards

Epithelium

Administration, Intranasal

Cystic Fibrosis Transmembrane Conductance Regulator

Defective Viruses - physiology

Virus Replication

Cystic Fibrosis - genetics

Genetic Vectors

Evaluation Studies as Topic

Genetic Therapy - adverse effects

Genetic Therapy - methods

Title: Subtitle: Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium
Creators: Michael J Welsh - Howard Hughes Medical Institute, Department of Internal Medicine, University of Iowa College of Medicine, Iowa City 52242
Alan E Smith
Joseph Zabner
Devra P Rich
Scott M Graham
Richard J Gregory
B M Pratt
Richard A Moscicki
Resource Type: Journal article
Publication Details: Human gene therapy, Vol.5(2), pp.209-219
Publisher: United States
DOI: 10.1089/hum.1994.5.2-209
PMID: 7514450
ISSN: 1043-0342
eISSN: 1557-7422
Language: English
Date published: 02/1994
Academic Unit: Neurology; Molecular Physiology and Biophysics; Pulmonary, Critical Care, and Occupational Medicine; Fraternal Order of Eagles Diabetes Research Center; Neurosurgery; Otolaryngology; Internal Medicine
Record Identifier: 9984006359802771

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