Journal article
Cytogenetic Abnormalities in B-Immunoblastic Lymphoma
Leukemia & lymphoma, Vol.14(5-6), pp.415-420
1994
DOI: 10.3109/10428199409049698
PMID: 7812201
Abstract
We have considered the cytogenetic abnormalities present in 27 unpublished cases of B-immunoblastic lymphoma. Among these 27 patients, the chromosome changes were heterogeneous and complex. The chromosomes most commonly gained were 3 (44% of cases), 18 (44%), 6 (30%) and 11 (30%). The most common structural abnormalities involved band 14q32 (26%), band 18q21 (15%) and bands 6q 16-21 (19%). Study of these 27 immunoblastic lymphomas did not allow us to tentatively identify a common primary cytogenetic abnormality unique to B-immunoblastic lymphoma, however, a translocation at 14q32 may be the primary cytogenetic lesion in some of the cases. Rather, we have added to the number of abnormalities reported in immunoblastic lymphoma and in non-Hodgkin's lymphoma in general.
Details
- Title: Subtitle
- Cytogenetic Abnormalities in B-Immunoblastic Lymphoma
- Creators
- Marcus B Nashelsky - 1Departments of Pediatrics, Meyer Rehabilitation Institute, Omaha, Nebraska, USAMichelle M Hess - 2Departments of Pathology, Microbiology, Omaha, Nebraska, USADennis D Weisenburger - 3Departments of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USAJene L Pierson - 4Department of Pathology, University of Missouri, Columbia Hospital and Clinics, Columbia, Missouri, USAMartin A Bast - 4Department of Pathology, University of Missouri, Columbia Hospital and Clinics, Columbia, Missouri, USAJames O Armitage - 4Department of Pathology, University of Missouri, Columbia Hospital and Clinics, Columbia, Missouri, USAWarren G Sanger - 2Departments of Pathology, Microbiology, Omaha, Nebraska, USA
- Resource Type
- Journal article
- Publication Details
- Leukemia & lymphoma, Vol.14(5-6), pp.415-420
- Publisher
- Informa UK Ltd
- DOI
- 10.3109/10428199409049698
- PMID
- 7812201
- ISSN
- 1042-8194
- eISSN
- 1029-2403
- Language
- English
- Date published
- 1994
- Academic Unit
- Epidemiology; Pathology
- Record Identifier
- 9984047656102771
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