Journal article
Cytokeratin changes in cell culture systems of epithelial cells isolated from oral mucosa: a short review
Italian journal of anatomy and embryology, Vol.110(2), pp.75-82
04/01/2005
PMID: 16277157
Abstract
In the past three decades, many studies have analyzed ultrastructural and molecular markers of differentiation in squamous stratified epithelial tissues. In these tissues, epithelial cells migrating from the basal layer to the upper layers undergo drastic changes, which involve membrane-associated proteins, DNA synthesis, phenotypic aspects, lipid composition, and cytoskeletal components. Cytoskeletal components include a large and heterogeneous group, including intermediate filaments, components of the cornified envelope, and of the stratum corneum. When grown in mono- and multilayer cell cultures, epithelial cells isolated from the oral mucosa may reproduce many of the biochemical and morphological aspects of epithelial tissue in vivo. In the present paper, we examine phenotypic changes, development of suprabasal layer, and Involucrin expression occurring in differentiating oral epithelial cells, based on literature review and original data.
Details
- Title: Subtitle
- Cytokeratin changes in cell culture systems of epithelial cells isolated from oral mucosa: a short review
- Creators
- Alberto GasparoniChristopher Alan SquierLuciano Fonzi
- Resource Type
- Journal article
- Publication Details
- Italian journal of anatomy and embryology, Vol.110(2), pp.75-82
- PMID
- 16277157
- ISSN
- 1122-6714
- Language
- English
- Date published
- 04/01/2005
- Academic Unit
- Oral Pathology, Radiology and Medicine; International Programs; Dental Clinic Administration
- Record Identifier
- 9984367750602771
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