Cytokine signaling to the cell cycle

Frederick W Quelle

doi:10.1007/s12026-007-0080-5

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Journal article

Peer reviewed

Cytokine signaling to the cell cycle

Frederick W Quelle

Immunologic research, Vol.39(1-3), pp.173-184

2007

DOI: 10.1007/s12026-007-0080-5

PMID: 17917064

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Abstract

The proliferation of many myeloid and lymphoid cell populations is directly controlled by cytokine growth factors acting through a related family of cytokine receptors. This regulation implies that the signaling pathways activated by cytokine receptors must communicate with mechanisms that control mammalian cell cycle progression. Evidence for how these signaling pathways promote hematopoietic cell proliferation is considered along with their likely targets among the cell cycle regulators.

Lymphocytes - metabolism

Cell Proliferation

Cytokines - metabolism

Signal Transduction

Humans

STAT Transcription Factors - metabolism

Intracellular Signaling Peptides and Proteins - metabolism

Lymphocytes - cytology

Phosphatidylinositol 3-Kinases - metabolism

Animals

Metabolic Networks and Pathways

Cell Cycle - physiology

Receptors, Cytokine - metabolism

Mitogen-Activated Protein Kinases - metabolism

Details

Title: Subtitle: Cytokine signaling to the cell cycle
Creators: Frederick W Quelle - Department of Pharmacology and The Graduate Program in Immunology, The University of Iowa, Carver College of Medicine, 2-210 Bowen Science Bld, Iowa City, IA 52242, USA. frederick-quelle@uiowa.edu
Resource Type: Journal article
Publication Details: Immunologic research, Vol.39(1-3), pp.173-184
Publisher: United States
DOI: 10.1007/s12026-007-0080-5
PMID: 17917064
ISSN: 0257-277X
eISSN: 1559-0755
Language: English
Date published: 2007
Academic Unit: Neuroscience and Pharmacology; Internal Medicine
Record Identifier: 9984040486302771

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