Cytokine storm in a massively burned pediatric patient

Mala Sharma; Lauren Roach; Ashleigh Bull; Leeanne Flygt; Zuhair Ballas; Alex Kurjatko; Madhuradhar Chegondi; Lucy Wibbenmeyer

doi:10.1093/jbcr/iraf007

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Cytokine storm in a massively burned pediatric patient

Journal article

Open access

Peer reviewed

Cytokine storm in a massively burned pediatric patient

Mala Sharma, Lauren Roach, Ashleigh Bull, Leeanne Flygt, Zuhair Ballas, Alex Kurjatko, Madhuradhar Chegondi and Lucy Wibbenmeyer

Journal of burn care & research, Vol.46(3), pp.674-677

08/12/2025

DOI: 10.1093/jbcr/iraf007

PMCID: PMC12344086

PMID: 39820414

Appears in UI Libraries Support Open Access

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Abstract

Cytokine storm can occur in many different clinical conditions and lack of recognition can lead to death. While cytokines have been measured and trended in burn patients, cytokine storm has not been widely discussed or its treatment reported. We present herein the diagnosis and the treatment of a 5-year-old, 91% burn patient, who developed cytokine storm three times during his hospital course. Aggressive treatment led to successful resolution. Cytokine storm should be entertained in patients who develop classic storm signs and symptoms, along with supporting laboratory. Treatment should be tailored to the patients' clinical picture. More study is warranted to define cytokine storm as well as its treatment in burn patients.

burn injury

pediatric burn injury

massive burn injury

cytokine storm

Meek micrografting

UIOWA OA Agreement

Details

Title: Subtitle: Cytokine storm in a massively burned pediatric patient
Creators: Mala Sharma - University of Iowa, Surgery
Lauren Roach - University of Iowa Stead Family Children’s Hospital
Ashleigh Bull - University of Iowa
Leeanne Flygt - University of Iowa, Critical Care
Zuhair Ballas - University of Iowa, Immunology
Alex Kurjatko - University of Iowa, Surgery
Madhuradhar Chegondi - University of Iowa, Stead Family Department of Pediatrics
Lucy Wibbenmeyer - University of Iowa
Resource Type: Journal article
Publication Details: Journal of burn care & research, Vol.46(3), pp.674-677
DOI: 10.1093/jbcr/iraf007
PMID: 39820414
PMCID: PMC12344086
NLM abbreviation: J Burn Care Res
ISSN: 1559-0488
eISSN: 1559-0488
Publisher: Oxford University Press; OXFORD
Language: English
Electronic publication date: 01/17/2025
Date published: 08/12/2025
Academic Unit: Critical Care; Stead Family Department of Pediatrics; Surgery; Injury Prevention Research Center; Immunology; Internal Medicine
Record Identifier: 9984773418802771

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