Journal article
Cytosolic innate immune sensing and signaling upon infection
Frontiers in microbiology, Vol.7, pp.313-313
2016
DOI: 10.3389/fmicb.2016.00313
PMCID: PMC4789553
PMID: 27014235
Abstract
Cytosolic sensing of pathogens is essential to a productive immune response. Recent reports have emphasized the importance of signaling platforms emanating from organelles and cytosolic sensors, particularly during the response to intracellular pathogens. Here, we highlight recent discoveries identifying the key mediators of nucleic acid and cyclic nucleotide sensing and discuss their importance in host defense. This review will also cover strategies evolved by pathogens to manipulate these pathways.
Details
- Title: Subtitle
- Cytosolic innate immune sensing and signaling upon infection
- Creators
- Lilliana Radoshevich - Institut Pasteur [Paris]Olivier Dussurget - Institut Pasteur [Paris]
- Resource Type
- Journal article
- Publication Details
- Frontiers in microbiology, Vol.7, pp.313-313
- DOI
- 10.3389/fmicb.2016.00313
- PMID
- 27014235
- PMCID
- PMC4789553
- NLM abbreviation
- Front Microbiol
- ISSN
- 1664-302X
- eISSN
- 1664-302X
- Publisher
- Frontiers Media
- Language
- English
- Date published
- 2016
- Academic Unit
- Molecular Physiology and Biophysics; Microbiology and Immunology
- Record Identifier
- 9984025448002771
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