Logo image
IRO Home Research units Researcher Profiles
Sign in
DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation
Journal article   Open access   Peer reviewed

DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation

S. Chalkias, M.R. Mackenzie, C. Gay, C. Dooley, F.M. Marty, R.B. Moss, T. Li, R.L. Routh, S.R. Walsh and C.S. Tan
Transplant infectious disease, Vol.16(1), pp.141-144
01/03/2014
DOI: 10.1111/tid.12177
PMCID: PMC4469988
PMID: 24383501
url
https://doi.org/10.1111/tid.12177View
Published (Version of record) Open Access

Abstract

Parainfluenza infection is a cause of significant morbidity and mortality in allogeneic hematopoietic stem cell transplant (HSCT) patients. DAS181 is a novel antiviral agent with activity against influenza and parainfluenza. We report the first 2 cases, to our knowledge, of successful DAS181 use in ventilated HSCT patients with severe parainfluenza lung disease.
DAS181 HSCT mechanical ventilation parainfluenza

Details

Metrics

Logo image