Journal article
DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program
Journal of the American Heart Association, Vol.7(9), e008089
05/01/2018
DOI: 10.1161/JAHA.117.008089
PMCID: PMC6015298
PMID: 29680824
Abstract
Background-While adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary Approach to Stop Hypertension (DASH) food pattern is associated with a lower risk of developing CAD among veterans.
Methods and Results-We analyzed data on 153 802 participants of the Million Veteran Program enrolled between 2011 and 2016. Information on dietary habits was obtained using a food frequency questionnaire at enrollment. We used electronic health records to assess the development of CAD during follow-up. Of the 153 802 veterans who provided information on diet and were free of CAD at baseline, the mean age was 64.0 (SD=11.8) years and 90.4% were men. During a mean follow-up of 2.8 years, 5451 CAD cases occurred. The crude incidence rate of CAD was 14.0, 13.1, 12.6, 12.3, and 11.1 cases per 1000 person-years across consecutive quintiles of Dietary Approach to Stop Hypertension score. Hazard ratios (95% confidence interval) for CAD were 1.0 (ref), 0.91 (0.84-0.99), 0.87 (0.80-0.95), 0.86 (0.79-0.94), and 0.80 (0.73-0.87) from the lowest to highest quintile of Dietary Approach to Stop Hypertension score controlling for age, sex, body mass index, race, smoking, exercise, alcohol intake, and statin use (P linear trend, <0.0001).
Conclusions-Our data are consistent with an inverse association between Dietary Approach to Stop Hypertension diet score and incidence of CAD among US veterans.
Details
- Title: Subtitle
- DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program
- Creators
- Luc Djousse - Harvard UniversityYuk-Lam Ho - The Huntington Library, Art Museum, and Botanical GardensXuan-Mai T. Nguyen - The Huntington Library, Art Museum, and Botanical GardensDavid R. Gagnon - Boston UniversityPeter W. F. Wilson - Atlanta VA Medical CenterKelly Cho - Harvard UniversityJ. Michael Gaziano - Harvard UniversityVA Million Veteran Program
- Contributors
- Zuhair K Ballas (Contributor) - University of Iowa, Immunology
- Resource Type
- Journal article
- Publication Details
- Journal of the American Heart Association, Vol.7(9), e008089
- DOI
- 10.1161/JAHA.117.008089
- PMID
- 29680824
- PMCID
- PMC6015298
- NLM abbreviation
- J Am Heart Assoc
- ISSN
- 2047-9980
- eISSN
- 2047-9980
- Publisher
- Wiley
- Number of pages
- 8
- Grant note
- G002 / award CSP I01-CX001025 / VA Merit Award; US Department of Veterans Affairs I01BX003340 / Veterans Affairs; US Department of Veterans Affairs
- Language
- English
- Date published
- 05/01/2018
- Academic Unit
- Immunology; Internal Medicine
- Record Identifier
- 9984359864202771
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