Journal article
DNA Polymerase Fidelity: Beyond Right and Wrong
Structure (London), Vol.24(11), pp.1855-1856
11/01/2016
DOI: 10.1016/j.str.2016.10.003
PMCID: PMC5486402
PMID: 27806256
Abstract
Accurate DNA replication depends on the ability of DNA polymerases to discriminate between correctly and incorrectly paired nucleotides. In this issue of Structure, Batra et al. (2016) show the structural basis for why DNA polymerases do not efficiently add correctly paired nucleotides immediately after incorporating incorrectly paired ones.
Details
- Title: Subtitle
- DNA Polymerase Fidelity: Beyond Right and Wrong
- Creators
- M Todd Washington - Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. Electronic address: todd-washington@uiowa.edu
- Resource Type
- Journal article
- Publication Details
- Structure (London), Vol.24(11), pp.1855-1856
- Publisher
- United States
- DOI
- 10.1016/j.str.2016.10.003
- PMID
- 27806256
- PMCID
- PMC5486402
- ISSN
- 0969-2126
- eISSN
- 1878-4186
- Grant note
- R01 GM081433 / NIGMS NIH HHS P30 CA086862 / NCI NIH HHS
- Language
- English
- Date published
- 11/01/2016
- Academic Unit
- Radiation Oncology; Biochemistry and Molecular Biology
- Record Identifier
- 9984024407702771
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