Journal article
DNA mapping of paired varicella-zoster virus isolates from patients with shingles
The Lancet (British edition), Vol.2(8361), pp.1223-1225
1983
DOI: 10.1016/s0140-6736(83)91271-0
PMID: 6139571
Abstract
Varicella-zoster virus (VZV) was isolated from two separate sites in each of three patients with shingles (herpes zoster). The DNAs of the six VZV isolates were compared by high-resolution restriction endonuclease analysis with HindIII, KpnI, and HpaI. DNA cleavage patterns for each pair of VZV isolates were indistinguishable. These studies suggest that clinical shingles is the manifestation of a single VZV strain that becomes reactivated and causes both a viraemia and a dermatomal exanthem.
Details
- Title: Subtitle
- DNA mapping of paired varicella-zoster virus isolates from patients with shingles
- Creators
- Barbara Pichini - Pennsylvania state univ., coll. medicineCharles Grose - Pennsylvania state univ., coll. medicineJoseph R Ecker - Pennsylvania state univ., coll. medicineRichard W Hyman - Pennsylvania state univ., coll. medicine
- Resource Type
- Journal article
- Publication Details
- The Lancet (British edition), Vol.2(8361), pp.1223-1225
- Publisher
- Lancet
- DOI
- 10.1016/s0140-6736(83)91271-0
- PMID
- 6139571
- ISSN
- 0140-6736
- eISSN
- 1474-547X
- Language
- English
- Date published
- 1983
- Academic Unit
- Stead Family Department of Pediatrics; Infectious Disease (Pediatrics)
- Record Identifier
- 9984093491902771
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