Journal article
DNA methylome: Unveiling your biological age
Protein & cell, Vol.4(10), pp.723-725
10/2013
DOI: 10.1007/s13238-013-3913-0
PMCID: PMC4875436
PMID: 24104390
Abstract
Hannum and colleagues performed DNA methylation sequencing to examine the relationship between DNA methylome and aging rate. Notably, they succeeded in building a quantitative and reproducible model based on the epigenetic bio-markers to predict aging rate with high accuracy. This progress enlightens us in many aspects particularly in applying this novel set of bio-markers on studying the mechanism of aging rate using adult tissue-specific stem cells, building up a potential quantitative model to explore the mechanism for other epigenetic factors like non-coding RNA, and understanding the principle and mechanism of 3D chromatin structure in epigenetic modulation.
Details
- Title: Subtitle
- DNA methylome: Unveiling your biological age
- Creators
- Ming Li - Beijing, 100101 ChinaWensu Liu - Beijing, 100101 ChinaTingting Yuan - Beijing, 100101 ChinaRuijun Bai - Beijing, 100101 ChinaGuang-Hui Liu - Beijing, 100101 ChinaWeizhou Zhang - Iowa City, IA 52242 USAJing Qu - Beijing, 100101 China
- Resource Type
- Journal article
- Publication Details
- Protein & cell, Vol.4(10), pp.723-725
- Publisher
- Higher Education Press
- DOI
- 10.1007/s13238-013-3913-0
- PMID
- 24104390
- PMCID
- PMC4875436
- ISSN
- 1674-800X
- eISSN
- 1674-8018
- Language
- English
- Date published
- 10/2013
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9984083873202771
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