Data on the utilization of paraneoplastic syndrome autoantibody testing at an academic medical center

Matthew D Krasowski; Anna Dolezal; Bryan W Steussy; Michael P Gailey; Benjamin W Darbro

doi:10.1016/j.dib.2021.107578

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Data on the utilization of paraneoplastic syndrome autoantibody testing at an academic medical center

Journal article

Open access

Peer reviewed

Data on the utilization of paraneoplastic syndrome autoantibody testing at an academic medical center

Matthew D Krasowski, Anna Dolezal, Bryan W Steussy, Michael P Gailey and Benjamin W Darbro

Data in brief, Vol.39, p.107578

12/2021

DOI: 10.1016/j.dib.2021.107578

PMCID: PMC8627986

PMID: 34877371

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Abstract

Paraneoplastic syndromes are rare conditions associated with characteristic autoantibodies produced by malignancy, although similar autoantibodies and clinical presentations may occur in the absence of any neoplasm. Testing for paraneoplastic syndromes often involves panels of autoantibody assays. While autoantibody testing may reveal or confirm actionable clinical diagnoses, inappropriate utilization of testing may be low yield and further lead to false positives that may confuse the clinical picture. There is thus opportunity to improve patient care by analyzing patterns of paraneoplastic autoantibody test utilization. The data in this article provides results from detailed retrospective review of patients tested by 7 autoantibody tests or test panels offered by two large reference laboratories in the United States. The data include 1,446 tests performed on 1,338 unique patients at an academic medical center. For all results, detailed chart review revealed main category of presenting symptoms, patient location at time of testing (either inpatient or outpatient), sex, age, whether cancer was present at the time of testing or later detected, and the specific results of the testing. The data are summarized by category of testing and specific autoantibodies.

Anti-N-methyl-D-aspartate receptor encephalitis

Autoantibodies

Paraneoplastic syndromes

Utilization review

Voltage-gated calcium channels

Voltage-gated potassium channels

Details

Title: Subtitle: Data on the utilization of paraneoplastic syndrome autoantibody testing at an academic medical center
Creators: Matthew D Krasowski - University of Iowa Hospitals and Clinics
Anna Dolezal - University of Iowa Hospitals and Clinics
Bryan W Steussy - University of Iowa Hospitals and Clinics
Michael P Gailey - University of Iowa Hospitals and Clinics
Benjamin W Darbro - University of Iowa
Resource Type: Journal article
Publication Details: Data in brief, Vol.39, p.107578
DOI: 10.1016/j.dib.2021.107578
PMID: 34877371
PMCID: PMC8627986
NLM abbreviation: Data Brief
ISSN: 2352-3409
eISSN: 2352-3409
Publisher: Elsevier Inc
Language: English
Date published: 12/2021
Academic Unit: Stead Family Department of Pediatrics; Pathology; Medical Genetics and Genomics
Record Identifier: 9984201254702771

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